Results 101 to 110 of about 7,930,152 (319)

Stellar Populations in the Local Group of Galaxies

open access: yes, 2005
The characteristics and properties of the stellar populations and evolutionary histories of Local Group galaxies are summarized and compared to predictions of cosmological models.
Grebel, Eva K.
core   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Multiple dynamical components in Local Group dwarf spheroidals

open access: yes, 2007
The dwarf spheroidal (dSph) satellites of the Local Group have long been thought to be simple spheroids of stars embedded within extended dark matter halos.
McConnachie, Alan W.   +2 more
core   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

The effectiveness of lunchbox interventions on improving the foods and beverages packed and consumed by children at centre-based care or school: a systematic review and meta-analysis

open access: yesInternational Journal of Behavioral Nutrition and Physical Activity, 2019
Objective To assess the effectiveness of lunchbox interventions aiming to improve the foods and beverages packed and consumed by children at centre-based care or school; and subsequent impact on children’s adiposity.
Nicole Nathan   +9 more
doaj   +1 more source

The Tidal Evolution of Local Group Dwarf Spheroidals

open access: yes, 2007
(Abridged) We use N-body simulations to study the evolution of dwarf spheroidal galaxies (dSphs) driven by galactic tides. We adopt a cosmologically-motivated model where dSphs are approximated by a King model embedded within an NFW halo.
Alan W. McConnachie   +11 more
core   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

A Systematic Review and Meta-Analysis of 16S rRNA and Cancer Microbiome Atlas Datasets to Characterize Microbiota Signatures in Normal Breast, Mastitis, and Breast Cancer

open access: yesMicroorganisms
The breast tissue microbiome has been increasingly recognized as a potential contributor to breast cancer development and progression. However, inconsistencies in microbial composition across studies have hindered the identification of definitive ...
Sima Kianpour Rad   +9 more
doaj   +1 more source

Symbiotic stars in the Local Group of Galaxies

open access: yes, 2015
Preliminary results of the ongoing search for symbiotic binary stars in the Local Group of Galaxies are presented and discussed.Comment: Proceedings of Physics of Evolved Stars 2015: A Conference Dedicated to the Memory of Olivier Chesneau, Nice, 8-12 ...
Caldwell, N.   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy