Results 121 to 130 of about 2,932,262 (319)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Journal of NeuroEngineering and RehabilitationBackground Technology is gaining momentum in rehabilitation. While evidence is emerging, a growing number of rehabilitation facilities are implementing devices, though with variable success.
Louise Michelle Nettleton Pearce +3 more
doaj +1 more source
ON THE LOCAL STRUCTURE OF THE REPRESENTATION OF A LOCAL GAUGE GROUP [PDF]
Infinite Dimensional Analysis, Quantum Probability and Related Topics, 2010 We discuss the local structure of the net [Formula: see text] of von Neumann algebras generated by a representation of a local gauge group [Formula: see text]. Our discussion is independent of the singularity of spectral measures, which has been discussed by many authors since the pioneering work of Gelfand–Graev–Veršic.
openaire +3 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Cooperation in local and global groups
, 2008 Multiple group memberships are the rule rather than the exception. Locally operating groups frequently offer the advantage of providing social recognition and higher marginal benefits to the individual, whereas globally operating groups may be more ...
Fellner, G., Luenser, G.
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
The impact of Sure Start Local Programmes on seven year olds and their families
, 2012 This research report presents the findings of a longitudinal study into the impact of Sure Start local programmes (SSLPs) on 7-year-olds and their families.
Belsky, Jay +4 more
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Geometric structure in smooth dual and local Langlands conjecture
This expository paper first reviews some basic facts about p-adic fields, reductive p-adic groups, and the local Langlands conjecture. If G is a reductive p-adic group, then the smooth dual of G is the set of equivalence classes of smooth irreducible ...
Aubert, Anne-Marie +3 more
core +1 more source
Evaluating local government performance in times of crisis
, 2019 In recent years, Spanish local governments have come under increasing pressure to accommodate severe economic restrictions while maintaining their provision of local public services.
Tortosa-Ausina, Emili +2 more
core +1 more source