Results 131 to 140 of about 27,475,594 (335)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Healthcare Workers Training Courses on Vaccinations: A Flexible Format Easily Adaptable to Different Healthcare Settings

open access: yesVaccines, 2020
Since 2017, Italy has expanded the compulsory vaccination from 4 to 10 for those aged 0 to 16 years. Because of the great organizational effort required for the immunization services, minor attention was given to the vaccinations not included among the ...
Laura Serino   +7 more
doaj   +1 more source

Homogeneous Locally Compact Groups

open access: yesJournal of Algebra, 1998
Motivated by their occurrence in topological geometry, the author studies locally compact groups that are homogeneous in the sense that their automorphism group acts transitively on the non-identity elements. The main results say that compact homogeneous groups are precisely the arbitrary powers of cyclic groups of prime order (with product topology ...
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Locally finite Sylp*-groups

open access: yesJournal of Algebra, 1984
This paper is a contribution to the study of locally finite groups satisfying Min-2, the minimal condition on 2-subgroups. Such a group G is called 2-fine, if the Sylow 2-subgroups of \(G/0_{2'2}(G)\) are finite. Conditions for a locally finite group with Min-2 to be 2-fine are important because they often enable problems about such groups to be ...
Stingl, Volker, Turau, Volker
openaire   +1 more source

Braided diagram groups and local similarity groups [PDF]

open access: yes, 2017
15 pages; 3 figures.
Farley, Daniel, Hughes, Bruce
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A Rigid Local System with Monodromy Group 2.J_2 [PDF]

open access: yes, 2018
We exhibit a rigid local system of rank six on the affine line in characteristic $p=5$ whose arithmetic and geometric monodromy groups are the finite group $2.J_2$ ($J_2$ the Hall-Janko sporadic group) in one of its two (Galois-conjugate) irreducible ...
Katz, Nicholas M., Rojas-León, Antonio
core   +1 more source

A local group differences test for subject-level multivariate density neuroimaging outcomes. [PDF]

open access: yesBiostatistics, 2021
Dworkin JD   +6 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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