Results 141 to 150 of about 17,303,555 (314)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Antea Group Archeologie 2019/85

, 2020
Antea Group 419859 Antea Group heeft op 4 oktober 2018 een archeologisch veldonderzoek (Opgraving, variant archeologische begeleiding) uitgevoerd op twee wierdeterreinen nabij Groot-Wetsinge.
Fens, R. (Antea Group), Tuinstra, S.J. (Antea Group), Sibma, T. (Antea Group)   +2 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Two decades of community-based conservation yield valuable insights into marine turtle nesting ecology

Oryx
For the Western Indian Ocean region, there is a significant knowledge gap regarding marine turtle nesting on the continental coast of East Africa. Here we present results from a long-term (2000–2020) community-based monitoring programme in and around ...
Casper H. van de Geer, Annette C. Broderick, Matt I.D. Carter, Athuman Abdallah Irei, Fikiri Kea Kiponda, Joseph Kiptum, Joe Ngunu Wandiga, Mohamed Omar, Nicola Parazzi, Hannah Sawyer-Kerr, Sam B. Weber, Ricardo Zanre, Brendan J. Godley   +12 more
doaj   +1 more source

Antea Group Archeologie 2016/54

, 2018
In opdracht van de gemeente Waalwijk heeft Antea Group in 2016 een archeologisch bureauonderzoek uitgevoerd naar de beschikbare archeologische gegevens met betrekking tot de Havenzone ten zuiden van de Rijksweg A59 te Waalwijk.
Koopmanschap, Dr. H.J.L.C. (Antea Group)
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Economies of Scale and Efficiency in the Wastewater Treatment Sector: A Decision Tree Approach

Applied Sciences
In this study, we use the efficiency analysis trees (EAT) model to evaluate the efficiency of wastewater treatment plants (WWTPs), focusing on identifying the key variables that enhance their performance.
Vicent Hernández-Chover, Águeda Bellver-Domingo, Lledó Castellet-Viciano, Francesc Hernández-Sancho   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The Role of Circular Economy Strategies in Promoting Sustainability in the Agri-Food Sector: Insights from the Valencian Community

Applied Sciences
The agri-food sector plays a pivotal role in the global economy, requiring innovative and efficient practices to ensure long-term sustainability. The paper aims to identify and analyse circular economy strategies applicable to the agri-food sector ...
Lledó Castellet-Viciano, Vicent Hernández-Chover, Águeda Bellver-Domingo, Francesc Hernández-Sancho   +3 more
doaj   +1 more source

Antea Group Archeologie 2017/42

, 2020
Antea Group Projectnummer 416276 Antea Group Archeologie heeft in april 2017 een archeologisch bureauonderzoek en inventariserend veldonderzoek uitgevoerd ten behoeve van de geplande werkzaamheden aan de Ulgersmaweg.
Tolsma, J. (Antea Group Archeologie), Fens, R.L. (Antea Group Archeologie)   +1 more
core   +1 more source