Results 161 to 170 of about 17,303,555 (314)

Bacterial Infections and Their Cell Wall Ligands Differentially Modulate Doxorubicin Sensitivity in Triple-Negative Breast Cancer Cells

Microorganisms
Background: Triple-negative breast cancer (TNBC) is an aggressive subtype with limited treatment options and poor clinical outcomes. Emerging evidence suggests that the tumor-associated microbiome may influence disease progression and therapy response ...
Sima Kianpour Rad, Runhao Li, Kenny K. L. Yeo, Fangmeinuo Wu, Yoko Tomita, Timothy J. Price, Wendy V. Ingman, Amanda R. Townsend, Eric Smith   +8 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

HST Proper Motions of Andromeda V and Andromeda VI

The Astrophysical Journal
We measure the absolute proper motions of Andromeda V (And V) and Andromeda VI/Pegasus (And VI) dwarf galaxies, satellites of M31 located near its galactic plane.
Dana I. Casetti-Dinescu, Marcel S. Pawlowski, Terrence M. Girard, Kosuke Jamie Kanehisa, Max Martone, Alexander Petroski   +5 more
doaj   +1 more source

The evolution of massive stars: bridging the gap in the Local Group. [PDF]

Philos Trans A Math Phys Eng Sci, 2017
Massey P, Neugent KF, Levesque EM.
europepmc   +1 more source

Antea Group Archeologie 2018/8

, 2018
In november/december 2017 (Haven 8-West) en februari 2018 (Haven 8-Oost) is door Antea Group in opdracht van de gemeente Waalwijk een inventariserend veldonderzoek, met proefsleuven. Dit voor het plangebied Haven 8 te Waalwijk.
Koopmanschap, Dr. H.J.L.C. (Antea Group)
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Globular clusters in high-redshift dwarf galaxies: a case study from the Local Group. [PDF]

Mon Not R Astron Soc, 2018
Zick TO, Weisz DR, Boylan-Kolchin M.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Big Local Partnership Reviews, 2015-2023

copyright UK Data Service and data collection copyright owner.Big Local is a long-term, place-based funding programme in England aimed at empowering residents in selected communities to lead local change, build community capacity, and improve outcomes ...
Local Trust
core   +1 more source