Results 61 to 70 of about 2,662,466 (269)

Long‐Term Outcomes of Patients With Relapsed/Refractory Neuroblastoma Treated on ANBL1221: A Report From the Children's Oncology Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Results of COG ANBL1221 changed treatment paradigms for patients with relapsed/refractory neuroblastoma. Chemoimmunotherapy with irinotecan/temozolomide/dinutuximab is now used as both bridge therapy following suboptimal response to induction and as treatment in first relapse.
Elizabeth Sokol, Arlene Naranjo, Lulu Chen, Rajen Mody, Steven G. DuBois, Rochelle Bagatell, Navin Pinto   +6 more
wiley   +1 more source

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen, Kristian Juul Sandahl, Lene Karlsson, Jonas Abrahamsson, Nira Arad‐Cohen, Daniel Cheuk, Barbara De Moerloose, Linda Fogelstrand, Jose Maria Fernandez Navarro, Bianca F. Goemans, Kirsi Jahnukainen, Gertjan Kaspers, Zhanna Kovalova, Monica Cheng Munthe‐Kaas, Ulrika Norén‐Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Tierens, Henrik Hasle, Kristian Løvvik Juul‐Dam   +21 more
wiley   +1 more source

Modeling the formation of ultra-faint dwarf spheroidal galaxies in an extreme collapsing scenario

Astronomy & Astrophysics
Context. The ultra-faint dwarf spheroidal galaxies (UFDs) around the Milky Way are the faintest, oldest, and most dark-matter-dominated systems known, providing an unique opportunity to understand early galaxy formation and how dark matter (DM) behaves ...
Vergara Landeros J. I., Fellhauer M., Matus Carrillo D., Cabello Cabello J. A.   +3 more
doaj   +1 more source

Resilience strategies of West African pastoralists in response to scarce forage resources

Pastoralism, 2021
Finding sufficient natural fodder resources to feed livestock has become a challenge for herders in the Sahel zone of Burkina Faso. Despite the existence of pastoral reserves, the issue of fodder shortage remains unsolved.
Karim Ouédraogo, Alhassane Zaré, Gabin Korbéogo, Oumarou Ouédraogo, Anja Linstädter   +4 more
doaj   +1 more source

T2* Magnetic Resonance Imaging Uncovers Hemosiderin Burden in Pediatric Hemophilia: A Call for Sensitive Imaging Biomarkers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hemophilic arthropathy remains the leading morbidity in hemophilia despite modern prophylaxis, and early joint damage may be missed by routine exams. This study explored T2* MRI as a noninvasive biomarker of hemosiderin deposition in pediatric hemophilia.
Jessica Garcia, Tarique Hussain, Jeanne Dillenbeck, Matthew Hammer, Annette von Drygalski, Guy Young, Ayesha Zia   +6 more
wiley   +1 more source

The dark fate of ultra-faint dwarfs: Gravothermal collapse in action

Astronomy & Astrophysics
Context. Ultra-faint dwarf (UFD) galaxies are a promising probe for dark matter (DM) physics as they are the most DM-dominated systems known. The Milky Way (MW) hosts many UFDs for which the properties of their DM distribution have been inferred from ...
Fischer Moritz S., Yu Hai-Bo
doaj   +1 more source

Survival by Race and Ethnicity in Children and Adolescents/Young Adults With Relapsed/Refractory Hodgkin Lymphoma: A Pooled Analysis of Children's Oncology Group Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Despite 5‐year survival rates of over 90% among children and adolescents/young adults (CAYAs) with classic Hodgkin lymphoma (cHL), 15%–20% relapse after frontline therapy. Prior analysis of frontline Children's Oncology Group (COG) clinical trials demonstrated that, despite similar rates of relapse, non‐Hispanic Black (NHB) and ...
Mallorie B. Heneghan, Lindsay A. Renfro, Yue Wu, Katia M. Crisler, Erin Marcotte, Tanya Trippett, Terzah Horton, Bradford S. Hoppe, Frank G. Keller, Chris Forlenza, Cindy Schwartz, Kara M. Kelly, Peter D. Cole, Sharon M. Castellino, Justine M. Kahn   +14 more
wiley   +1 more source

A note on the localization of $J$-groups

Hiroshima Mathematical Journal, 1999
Let $\widetilde{JO}(X)=\widetilde{KO}(X)/TO(X)$ be the J-group of a connected finite CW complex X. We Obtain two computable formulas of $TO(X)_{(p)}$, the localization of $TO(X)$ at a prime p. Then we show how to use these two formulas of $TO(X)_{(p)}$ to find the J-orders of elements of $\widetilde{KO}(CP^m)$, at least the 2 and 3 primary factors of ...
openaire   +3 more sources

Childhood Acute Lymphoblastic Leukemia Survival in Western Kenya: Reduction in Early Deaths and Treatment Abandonment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An earlier study on children diagnosed with acute lymphoblastic leukemia (ALL) at Moi Teaching and Referral Hospital (MTRH) in Kenya reported a low event‐free survival (EFS), excess treatment abandonment, and high induction mortality.
Gilbert Olbara, George Bogonko, Festus Njuguna, Sandra Langat, Martha Kipngetich, Dennis Njenga, Gertjan Johannes Kaspers, Terry Allen Vik   +7 more
wiley   +1 more source

Defining a mood stabiliser: novel framework for research and clinical practice

BJPsych Open, 2018
The term ‘mood stabiliser’ is ill-defined and lacks clinical utility. We propose a framework to evaluate medications and effectively communicate their mood stabilising properties – their acute and prophylactic efficacy across the domains of mania and ...
Gin S. Malhi, Richard Porter, Lauren Irwin, Amber Hamilton, Grace Morris, Darryl Bassett, Bernhard T. Baune, Philip Boyce, Malcolm J. Hopwood, Roger Mulder, Gordon Parker, Zola Mannie, Tim Outhred, Pritha Das, Ajeet B. Singh   +14 more
doaj   +1 more source