The relationship between local scalp skin temperature and cutaneous perfusion during scalp cooling [PDF]
Cooling the scalp during administration of chemotherapy can prevent hair loss. It reduces both skin blood flow and hair follicle temperature, thus affecting drug supply and drug effect in the hair follicle. The extent to which these mechanisms contribute
Janssen, Francis-Paul E.M. +4 more
core +4 more sources
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Method for Characterization of Material Loss from Modular Head-Stem Taper Surfaces of Hip Replacement Devices [PDF]
Assessment of the head-stem taper junction requires the estimation of material loss from the taper surfaces of both femoral head and stem. This paper describes a method for the measurement and analysis of material loss from the modular taper junction of ...
Bills +19 more
core +1 more source
Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
Low-head dams are ubiquitous human disturbances that degrade aquatic ecosystem function worldwide. The localized effects of low-head dams have been relatively well documented; however, most previous studies have ignored the concealed process caused by ...
Qiang Li +7 more
doaj +1 more source
EFFECT OF INLET AND OUTLET GEOMETRIC SHAPE VARIATIONS OF A PIPE CULVERT ON LOCAL HEAD-LOSSES [PDF]
This research investigates the losses resulting from the sudden contraction and expansion of a pipe culvert. A four hundred runs were carried out considering various angles and contraction ratios at inlet and outlet of the pipe culvert and downstream submerged ratios with different flow conditions. Results were analyzed and graphically presented.
openaire +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Localizing by Describing: Attribute-Guided Attention Localization for Fine-Grained Recognition
A key challenge in fine-grained recognition is how to find and represent discriminative local regions. Recent attention models are capable of learning discriminative region localizers only from category labels with reinforcement learning.
Ding, Errui +4 more
core +1 more source
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source
Synthetic aperture radar (SAR), with its all-weather and all-day observation capabilities, plays a significant role in the field of remote sensing. However, due to the unique imaging mechanism of SAR, its interpretation is challenging.
Cheng Xu, Yingying Kong
doaj +1 more source

