Results 71 to 80 of about 2,033,218 (305)

Penza region during the Great Patriotic War: integration challenges

open access: yesИзвестия высших учебных заведений. Поволжский регион: Гуманитарные науки, 2022
Background. The relevance of developing the problem is determined by the need to comprehend the process of glocalization – strengthening the value of local specificity, its actualization.
V.Yu. Kladov   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

DGS Newsletter

open access: yes, 1976
Monthly newsletter of the Local History & Genealogical Society discussing membership, Society meetings, genealogical workshops and events, and other news of interest to ...
Local History and Genealogical Society (Dallas, Tex.)
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Geography of Voyages of Louis XI and the Count of Charolais during the Confrontation between the King and the “League of the Public Welfare”

open access: yesИсторико-географический журнал
The article is devoted to the events of 1465 in France, when the fate of the future political structure of the kingdom was being decided in the confrontation between the King of France Louis XI and the “League of the Public Welfare”, headed by the Count ...
А. V. Verbovskiy, E. S. Grishin
doaj   +1 more source

Andreev Ivan Fedorovych, a researcher of the fauna of Bukovyna [PDF]

open access: yesNovitates Theriologicae, 2022
Ivan Andreev was a researcher highly motivated for social and leadership activities (work in the Komsomol, party cells, propaganda departments, the Institute of the Red Professorship, head of both the zoological museum and department, supporter of ...
Igor Zagorodniuk, Igor Skilsky
doaj  

Belgian refugees in World War 1: local archives & histories

open access: yes, 2016
Twentieth century world wars led to many refugees seeking sanctuary from violence and persecution in other countries. Yet our knowledge and interest in these population displacements is far from consistent.
Rebecca, Gill
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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