Results 91 to 100 of about 3,820,279 (302)

Web 2.0 and knowledge management for local government in England – A model for the public sector? [PDF]

open access: yes, 2009
PURPOSE Delivering success in the public and private sector requires staff to have access to the best knowledge possible about how to do their jobs well so a major challenge for employers is how to ensure their staff are making decisions based on the ...
Leask, M
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

DOES THE LOCAL ECONOMIC GOVERNANCE IN INDONESIAPERFORM AN IMPROVEMENT?

open access: yesBuletin Ekonomi Moneter dan Perbankan, 2012
Governance has gone through radical changes over the last twenty five years. Seemingly, it became one of the important strategies, processes, methods and mechanisms in governing countries to achieve economic development goals. The objective of this paper
Haryo Kuncoro
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Local Area Improvement of GSM Network Coverage

open access: yesEngineering Proceedings
This article describes the design of a local GSM signal amplifying system and presents the results of appliance performance measurements, simulations and analyses.
Miroslav Tomov   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Metabolic Engineering for Enhanced Medium Chain Omega Hydroxy Fatty Acid Production in Escherichia coli

open access: yesFrontiers in Microbiology, 2018
Medium chain hydroxy fatty acids (HFAs) at ω-1, 2, or 3 positions (ω-1/2/3) are rare in nature but are attractive due to their potential applications in industry. They can be metabolically engineered in Escherichia coli, however, the current yield is low.
Kang Xiao   +16 more
doaj   +1 more source

Data-Informed Leadership in Education [PDF]

open access: yes, 2006
Explores ideas, frameworks, and beliefs concerning the use of data in educational decision making and in the work of leaders at state and local levels as it relates to the improvement of teaching and ...
Jack Monpas-Huber   +3 more
core  

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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