Results 111 to 120 of about 3,820,279 (302)

Norm groups and class fields of formally real quasilocal fields

open access: yes, 2008
This paper establishes a relationship between finite extensions and norm groups of formally real quasilocal fields, which yields a generally nonabelian local class field theory, including analogues to the fundamental correspondence, the local reciprocity
Chipchakov, I. D.
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Characterizing withdrawal from long-acting injectable buprenorphine: An observational case series

open access: yesDrug and Alcohol Dependence Reports
Introduction: Long-acting injectable buprenorphine (LAIB) products are being increasingly used to treat patients with opioid dependence. Limited data is available on the severity or timespan (time to onset, peak, duration) of withdrawal signs and ...
Victoria Hayes   +8 more
doaj   +1 more source

Tight asymptotic key rate for the BB84 protocol with local randomisation and device imprecisions

open access: yes, 2014
Local randomisation is a preprocessing procedure in which one of the legitimate parties of a quantum key distribution (QKD) scheme adds noise to their version of the key and was found by Kraus et al. [Phys. Rev. Lett.
Woodhead, Erik
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Density-Functional-Based Determination of the CH3-CH4 Hydrogen Exchange Reaction Barrier

open access: yes, 1994
Due to the overbinding that is inherent in existing {\em local} approximations to the density-functional formalism, certain reaction energies have not been accessible.
Andzelm   +35 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Challenges and opportunities in genetic improvement of local livestock breeds

open access: yesFrontiers in Genetics, 2015
Sufficient genetic variation in livestock populations is necessary both for adaptation to future changes in climate and consumer demand, and for continual genetic improvement of economically important traits.
Filippo eBiscarini   +4 more
doaj   +1 more source

Local Development and the Role of Small Towns in Space Organisation in Contemporary Poland [PDF]

open access: yes, 2014
Published in: Origin Spatial Development of Contemporary Poland in Łódź University Geographical Research, edited by T.MarszałThe majority of small towns are undertaking efforts to redefine their role and position in the spatial structure of the region ...
Kobojek, Elżbieta, Marszał, Tadeusz
core  

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