Results 31 to 40 of about 7,252,073 (249)

D7.4 - MAGNITUDE Policy Recommendations

open access: yes, 2021
This report is Deliverable D7.4 of the MAGNITUDE H2020 European proejct.The objective is to deliver policy recommendations in a pan-European perspective and to provide inputs to the ongoing policy discussions in the energy field.
Corscadden, Jack   +8 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

A Magnitude Effect in Temporal discounting with Hens [PDF]

open access: yes, 2014
This study aimed to determine whether a magnitude effect could be obtained in temporal discounting with brown shaver hens. Subjects responded in a classic self-control situation for the choice between a smaller-sooner reward (1-s access to food, after a ...
Budenberg, Grace Joy
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Calibration of local earthquake magnitudes in Nepal

open access: yesJournal of Nepal Geological Society, 2011
An attempt has been made to calibrate magnitudes of local earthquakes recorded by National Seismological Centre (NSC) of the Department of Mines and Geology (DMG), Nepal with other magnitudes of corresponding earthquakes [eported by International Seismological Centre (ISC), UK, and United States Geological Survey (USGS), USA.
S. Rajaure   +3 more
openaire   +2 more sources

EVERY REINFORCER COUNTS: REINFORCER MAGNITUDE AND LOCAL PREFERENCE [PDF]

open access: yesJournal of the Experimental Analysis of Behavior, 2003
Six pigeons were trained on concurrent variable‐interval schedules. Sessions consisted of seven components, each lasting 10 reinforcers, with the conditions of reinforcement differing between components. The component sequence was randomly selected without replacement.
Michael, Davison, William M, Baum
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Supplementary Material 2: Calculated frequency-magnitude estimates

open access: yes, 2023
Supplementary Material 2: Calculated frequency-magnitude estimates of Hayes, J.L., Jenkins, S.F., Joffrain, M., 2022. Large uncertainties are pervasive in long-term frequency-magnitude relationships for volcanoes in Southeast Asia.
Jenkins, Susanna   +2 more
core   +1 more source

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