Results 51 to 60 of about 4,363,339 (298)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mediating Power-to-X: A case study of green imaginaries and environmental conflicts in local Danish news media

open access: yesNordicom Review
Recently, Power-to-X (PtX) has come to play a prominent role in the public discussion of a green energy future, with high hopes expressed by political and business players.
Horsbøl Anders
doaj   +1 more source

Disinformation and Local Media in the Iberian Context: How to Protect News Credibility

open access: yesJournalism and Media
Regional and local media outlets have much more credibility than news organizations placed at a national level, according to polls. In a context fueled by the spread of disinformation, audiences seem to trust close journalistic sources, while national ...
Ángeles Fernández-Barrero   +2 more
doaj   +1 more source

City Magazines and Social Media: Moving beyond the Monthly [PDF]

open access: yes, 2013
City magazines have long been established in many American locales, but digital media of all types are now offering opportunities and challenges to this genre of magazine.
Sivek, Susan Currie
core   +1 more source

Non-local Multi-continua Upscaling for Flows in Heterogeneous Fractured Media

open access: yes, 2017
In this paper, we propose a rigorous and accurate non-local (in the oversampled region) upscaling framework based on some recently developed multiscale methods [10].
Chung, Eric T.   +4 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

The ethics of journalism challenged

open access: yesJournalistica, 2022
The article examines Finnish news professionals’ views on the ethical challenges that ensue from emerging and intertwining forms of local professional journalism and communications. Besides describing the current situation, the article employs data from
Jaana Hujanen   +4 more
doaj   +1 more source

Anderson localization in anisotropic random media [PDF]

open access: yesPhysical Review B, 1990
Etude analytique et numerique de la localisation d'Anderson dans les systemes dans lesquels le caractere aleatoire est anisotrope et intermediaire entre differentes dimensions. En fonction du parametre d'anisotropie θ, qui s'intercalle entre un systeme aleatoire en couches unidimensionnel et le caractere aleatoire isotrope tridimensionnel, les ...
Zhang, Zhaoqing   +3 more
openaire   +3 more sources

Fiber-optical analogue of the event horizon

open access: yes, 2008
The physics at the event horizon resembles the behavior of waves in moving media. Horizons are formed where the local speed of the medium exceeds the wave velocity.
Brabec   +13 more
core   +1 more source

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