Results 241 to 250 of about 6,352,807 (298)

CAR‐Engineered Cell Therapies Beyond Cancer: Reprogramming Fibrosis and Immune‐Mediated Inflammation

Advanced Science, EarlyView.
CAR‐engineered cell therapies are expanding beyond cancer toward immune resetting, pathological‐cell clearance, matrix remodeling, and microenvironmental reprogramming in autoimmune, inflammatory, and fibrotic diseases. This Review compares CAR‐T, CAR‐macrophage, and CAR‐NK platforms and proposes controllable spatiotemporal reprogramming to align ...
Peng Jun Xu, Zhou Jing Zhang, Jing Jin, Hai Yuan Xu, Ya Xin Gu, Qian Qian Yang, You Lang Zhou   +6 more
wiley   +1 more source

Extensive Giant Cell Tumor Involving Entire Tibia with Talar Extension and Pulmonary Metastases: Successful Limb Preservation with Denosumab and Angioembolization. [PDF]

J Orthop Case Rep
Kumar P, Tandon N, Nishith N, Gulia A.
europepmc   +1 more source

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

Inflammatory myofibroblastic tumor of the larynx: a case report. [PDF]

Front Oncol
Reithofer M, Pesto L, Hütten T, Jurejevcic A, Rößmann-Tsybrovskyy M, Tervonen H, Thurnher D.   +6 more
europepmc   +1 more source

Radiation‐Triggered Chemokine‐Secreting Probiotics for Boron Neutron Capture Therapy Based Radioimmunotherapy

Advanced Science, EarlyView.
Engineered Escherichia coli Nissle 1917 with a tannic acid‐mediated BPA coating enables tumor‐targeted boron delivery for BNCT. The low‐level incidental radiation generated during BNCT activate a RecA‐driven circuit to induce CXCL10, while radiation‐enhanced bacterial colonization triggers in situ vaccination and systemic antitumor immunity.
Yang Liu, Yuzhong Qian, Shaobo Huang, Bingbing Li, Yue Yu, Xiang Cheng, Chang Chen, Jiheng Wang, Maosong Yang, Lizheng Liang, Xiancai Meng, Zhigang Liu   +11 more
wiley   +1 more source

Low-grade appendiceal mucinous neoplasm vs. high-grade appendiceal mucinous neoplasm: similarities, differences, and current management challenges. [PDF]

Contemp Oncol (Pozn)
Lesiak P, Kapturkiewicz B, Jastrzębski T, Bębenek M, Kazanowski M.   +4 more
europepmc   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source

Incidence Proportion and Clinicopathological Characteristics of Phyllodes Tumors of the Breast Among Patients With Breast Lumps in Dubai, 2017-2022: A Retrospective Observational Study. [PDF]

Cureus
Alsayed O, Siddiqi W, Saber A.
europepmc   +1 more source

Primary Soft Tissue Sarcomas of the Extremities: A Nationwide Retrospective Cohort Study of Histology-Specific Outcomes and Prognostic Factors. [PDF]

Cancers (Basel)
Novak M, Perhavec A, Supe BN, Blatnik O, Vidmar MS, Unk M, Kramer S, Marušič S, Ramanović M.   +8 more
europepmc   +1 more source

Recurrent Case of Microcystic Adnexal Carcinoma Arising From the External Auditory Canal: A Case Report. [PDF]

Clin Case Rep
Enam A, Zaidi H, Tanveer M, Khyani IAM, Hidig SM.   +4 more
europepmc   +1 more source