Results 161 to 170 of about 48,666 (293)

Cancer‐Associated Fibroblasts Promote Tumor Immunosuppression in Hepatocellular Carcinoma via the NNMT‐ANGPTL4 Axis

Advanced Science, EarlyView.
ABSTRACT Background & Aims: Cancer‐associated fibroblasts (CAFs) drive immunosuppression in hepatocellular carcinoma (HCC). However, their metabolic regulation remains poorly defined. We investigated the role of nicotinamide N‐methyltransferase (NNMT) in CAFs. Approach & Results: High NNMT expression in CAF tissues was confirmed by western blotting and
Shounan Lu, Shanjia Ke, Hongjun Yu, Zhanzhi Meng, Miaoyu Bai, Yanan Xu, Hui Zhu, Jinwen Yang, Baolin Qian, Bing Yin, Chaoqun Wang, Zhigang Feng, Zhongyu Li, Yongzhi Zhou, Zihao Li, Xinglong Li, Yongliang Hua, Yao Fu, Wei Tang, Yaohua Wu, Yong Ma   +20 more
wiley   +1 more source

RISE-VIO: Robust Initialization and Targeted Pose Robustification for INS-Centric Visual-Inertial Odometry Under Degraded Visual Conditions. [PDF]

Sensors (Basel)
Xu X, Ju R, Jiao W, Li L.
europepmc   +1 more source

Non-Destructive Inspection on Resin Grouting Judgement for Repaired RC Member by Local Outlier Factor Method

Toshiomi Nishi, Michie Koga, Shigeyuki HIRO, Ichiro Kuroda   +3 more
openalex   +1 more source

Local Outlier Factor based Data Mining Model for Three Phase Transmission Lines Faults Identification

, 2015
Tan Yong, Emran Bin, Pratap Nair, Raman Raguraman, K. Nithiyananthan   +4 more
openalex   +1 more source

Detecting outliers in rule-based knowledge bases using Self-Organizing Map and Local Outlier Factor algorithms

Procedia Computer Science, 2023
Czeslaw Horyn, Agnieszka Nowak-Brzezinska   +1 more
openaire   +1 more source

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

Advanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao, Ruixue Nie, Hailu Fan, Tenzin Ngodroup, Li Zhu, Hongbin Pan, Bo Zhang, Hao Zhang   +7 more
wiley   +1 more source

A Novel Peak-Shape Aware Approach for Mass Alignment in Mass Spectrometry. [PDF]

Rapid Commun Mass Spectrom
Vanhemel T, Nijs M, Birmpili A, Hendriks TFE, Cuypers E, De Moor B.   +5 more
europepmc   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Dams and Introduced Species Drive Patterns of Environmental Adaptation in an Iconic but Imperiled Coldwater Fish (Brook Trout, <i>Salvelinus fontinalis</i>). [PDF]

Evol Appl
Mamoozadeh N, Cooper A, Quinlan H, Varian A, Infante D, Meek M.   +5 more
europepmc   +1 more source

A Hierarchical Framework Using Approximated Local Outlier Factor for Efficient Anomaly Detection

, 2013
Lin Xu, Yi-Ren Yeh, Yuh‐Jye Lee, Jing Li   +3 more
openalex   +1 more source