Results 81 to 90 of about 5,469,672 (300)
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
This paper examines the role of local press as institution that supports democracy in regional level, in decentralisation era. As an entry point, this paper uses the media coverage of Dana Keistimewaan in Tribun Jogja daily newspaper, a non-partisan ...
Niti Bayu Indrakrista
doaj +1 more source
Sliding Objects with Random Friction
We study the motion of elastic networks driven over a random substrate. Our model which includes local friction forces leads to complex dynamical behavior. We find a transition to a sliding state which belongs to a new universality class.
Bak +26 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
ON FUNKTIONAL MISSION OF THE CONTEMPORARY LOCAL PRESS (EXAMPLIFIED BY THE STAVROPOL TERRITORY PRESS)
The article discusses the role of contemporary local press in localized information space. The author reveals the actual contradiction in typological characteristics of local periodicals, which prevents this type of the press from performing its main ...
M. Korneeva
doaj
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
1960’DAN GÜNÜMÜZE KONYA’DA YEREL GAZETECİLİK
Bu çalışma Türk basınının kırılma noktalarından biri olan 1960’dan bugüne Konya yerel basınıhakkında bilgi vermeyi amaçlamaktadır. Ulusal basının aksine yerel basın yapılanma ve içerik olarak oldukça zayıf ve geridir.
Bünyamin Ayhan, Adem Demirsoy
doaj
Superdense and normal early-type galaxies at 1
We combined proprietary and archival HST observations to collect a sample of 62 early-type galaxies (ETGs) at 0 ...
Gargiulo, A., Longhetti, M., Saracco, P.
core +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Reconstructing the Narrative of Rape in the Kibbutz by the Israeli Press
The author proposes that national press coverage of sex crimes in Israeli kibbutzim is intended to restructure the public’s perception by showing that such crimes are a symptom of broader social problems. Articles about a rape incident in Kibbutz Shomrat
Efrat Shoham
doaj +3 more sources

