Results 61 to 70 of about 1,764 (213)
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Reconstructing the Narrative of Rape in the Kibbutz by the Israeli Press
The author proposes that national press coverage of sex crimes in Israeli kibbutzim is intended to restructure the public’s perception by showing that such crimes are a symptom of broader social problems. Articles about a rape incident in Kibbutz Shomrat
Efrat Shoham
doaj +3 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
This article aims to analyze the publicization of debates on public policy orientations, sociotechnical choices, and alternative solutions proposed by stakeholders to address situations of drought and water scarcity.
Anne-Lise Boyer +2 more
doaj +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Latin America’s Transformative New Extraction and Local Conflicts
Subterranean Struggles: New Dynamics of Mining, Oil, and Gas in Latin America, edited by Anthony Bebbington and Jeffrey Bury. University of Texas Press, 2013.Unearthing conflict: Corporate Mining, Activism, and Expertise in Peru, by Fabiana Li.
Barbara Hogenboom
doaj +1 more source
Presse locale, un média de diversion [PDF]
L’information locale en France est, en apparence, diverse et neutre. Une analyse de contenu de la presse régionale bretonne montre au contraire qu’elle demeure marquée par une vision du monde très hiérarchisée et privilégiant la stabilité sociale. D’une société faite d’interrelations et de processus dynamiques, elle ne retient qu’une juxtaposition de ...
openaire +3 more sources
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Introducción: El artículo analiza las fuentes del conocimiento en el proceso de enseñanza-aprendizaje de la Historia y las potencialidades de los textos periodísticos.
Jhoannis Jacinto Rodríguez Avalos +5 more
doaj

