Results 41 to 50 of about 19,832,793 (263)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Presse régionale et multisupports
Tic & Société, 2012 This article retraces the path followed by a regional daily in France in diversifying its activities and enlisting its workers in the task of mastering a multichannel journalism.
Denis RUELLAN, Joël LANGONNE
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Observations and views of women in managerial positions in local media [PDF]
Published online: 28 February 2025The study collects and analyzes data on the perceptions and views of women in managerial positions in local media in Serbia.
MEDIĆ, Duško, BLAGOJEV, Tijana
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
1960’DAN GÜNÜMÜZE KONYA’DA YEREL GAZETECİLİK
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2005 Bu çalışma Türk basınının kırılma noktalarından biri olan 1960’dan bugüne Konya yerel basınıhakkında bilgi vermeyi amaçlamaktadır. Ulusal basının aksine yerel basın yapılanma ve içerik olarak oldukça zayıf ve geridir.
Bünyamin Ayhan, Adem Demirsoy
doaj
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Osmaniye Yerel Basının Dijital Dönüşüm Çerçevesinde Eleştirel Ekonomi Politiği
İletişim Kuram ve Araştırma DergisiAraştırma, Osmaniye yerel basınının dijitalleşme sürecinde ekonomi politik yapısındaki değişimi ortaya koymayı amaçlamaktadır. Araştırmanın temel problemi, Osmaniye yerel basınının ekonomi politik yapısı dijitalleşmeyle birlikte değişime tabi olmuş mudur?
Gülsüm Şimşek
doaj +1 more source