Results 51 to 60 of about 19,832,793 (263)
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
МЕСТНЫЕ СМИ И ВЛАСТЬ: ВЗАИМОДЕЙСТВИЕ В ПЕРИОД ВЫБОРОВ (НА МАТЕРИАЛЕ ПРЕССЫ МУРМАНСКОЙ ОБЛАСТИ)
Часть мурманских средств массовой информации находятся под контролем органов государственного управления, так как имеют в качестве учредителя муниципальные органы власти. Этот контроль особо проявляется во время проведения предвыборных кампаний, которые,
Olga Nikolajevna Ivanishcheva
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Local press problems in facing the contestation of the election of Regional Heads in West Sumatra Province can be grouped into two broad lines: first, the local press is dragged into a conflict of interest in the election of the Regional Head including 1)
Icol Dianto
doaj +1 more source
The Indian Ocean and its implications for a Global Intellectual History of Political Economy
Books under review: Johan Mathew, Margins of the Market. Trafficking and Capitalism across the Arabian Sea (Oakland, CA: University of California Press, 2016) Fahad A. Bishara, A Sea of Debt.
Mattia Steardo
doaj +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
The article shows the role of the Polish press in the military conflict between Poland and Czechoslovakia about Cieszyn Silesia that took place in January and February 1919. The press at that time was of key significance due to many reasons.
Grzegorz Wnętrzak
doaj +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Research on the pressures on local media in Serbia : period July 2022-May 2024
Published: 24 June 2024The aim of the research is to review and analyze the forms and sources of systemic and individual pressures on the local media that members of "Local Press" had in the period from July 2022 to May 2024, defining their position and ...
MEDIĆ, Duško +2 more
core +1 more source

