Results 31 to 40 of about 597,566 (313)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

„GAZETA NIDZICKA” (1990–2001). POWSTANIE – REDAKCJA – FORMUŁA WYDAWNICZA

open access: yesCivitas et Lex, 2018
The article focuses on the presentation of the beginning, editor-in-chiefs, publishers, publishing formulas and graphic layout and typographic layout of “Gazeta Nidzicka” in 1990−2001, ie during the period of the publication of the magazine.
Wojciech Guzewicz, KAROLINA Turowska
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

The Media Protest of Neighbouring Associations, Promoter of Citizen Democratic Culture during Transition in Southern Spain

open access: yesMedia and Communication, 2018
In the current context of placing value on the neighbouring movement within the Spanish democratic Transition, we set out to confirm that the press actively participates in the growing conjunction of neighbouring issues with political content and ...
Sandra Méndez-Muros
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

YEREL KAMUOYUNUN OLUŞUMUNDA YEREL BASININ ROLÜ -TRABZON ÖRNEĞİNDE BİR ARAŞTIRMA-

open access: yesSelçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2008
Uluslararasıve ulusal kamuoyunu oluşturan öğeler içerisinde yer almakla birlikte belirli bir yörede yaşayan insanlardan oluşan yerel kamuoyu, kapsamıve niteliği itibariyle daha lokal boyutlarda oluşmaktadır.
Onur Bekiroğlu
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Kıbrıs Meselesinin Yerel Basına Yansımaları (1950-1960): Vansesi Gazetesi Örneği

open access: yesYüzüncü Yıl Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2021
Kıbrıs, tarihsel süreç içerisinde Akdeniz’de varlık gösteren bütün devletler için çok önemli olmuştur. Osmanlı Devleti, bu adanın Anadolu topraklarını savunmasındaki rolünü iyi bildiği için buradaki hâkimiyete çok önem vermiştir.
Mehmet Özalper
doaj  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Political management in Australian local government exploring roles and relationships between Mayors and CEOs [PDF]

open access: yes, 2012
This discussion paper explores the dimensions of models that define working relationships between council Mayors and members of local government.The working relationship between the Mayor as the leader of the council and the chief executive officer (CEO)
Chris Aulich   +3 more
core  

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