Results 31 to 40 of about 19,832,793 (263)
Mobile Applications Accessibility: An Evaluation of the Local Portuguese Press
Informatics, 2021 The local press has always played a central role in the Portuguese society. Recently, new innovative technological projects to develop mobile applications and focus on local journalism in Portugal have emerged.
Tatiana Santos Gonçalves +2 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
„GAZETA NIDZICKA” (1990–2001). POWSTANIE – REDAKCJA – FORMUŁA WYDAWNICZA
Civitas et Lex, 2018 The article focuses on the presentation of the beginning, editor-in-chiefs, publishers, publishing formulas and graphic layout and typographic layout of “Gazeta Nidzicka” in 1990−2001, ie during the period of the publication of the magazine.
Wojciech Guzewicz, KAROLINA Turowska
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
YEREL KAMUOYUNUN OLUŞUMUNDA YEREL BASININ ROLÜ -TRABZON ÖRNEĞİNDE BİR ARAŞTIRMA-
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2008 Uluslararasıve ulusal kamuoyunu oluşturan öğeler içerisinde yer almakla birlikte belirli bir yörede yaşayan insanlardan oluşan yerel kamuoyu, kapsamıve niteliği itibariyle daha lokal boyutlarda oluşmaktadır.
Onur Bekiroğlu
doaj
Media and Communication, 2018 In the current context of placing value on the neighbouring movement within the Spanish democratic Transition, we set out to confirm that the press actively participates in the growing conjunction of neighbouring issues with political content and ...
Sandra Méndez-Muros
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Kıbrıs Meselesinin Yerel Basına Yansımaları (1950-1960): Vansesi Gazetesi Örneği
Yüzüncü Yıl Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2021 Kıbrıs, tarihsel süreç içerisinde Akdeniz’de varlık gösteren bütün devletler için çok önemli olmuştur. Osmanlı Devleti, bu adanın Anadolu topraklarını savunmasındaki rolünü iyi bildiği için buradaki hâkimiyete çok önem vermiştir.
Mehmet Özalper
doaj
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source