Results 51 to 60 of about 702,297 (217)

Systemic and Local Administration of Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells Promotes Fracture Healing in Rats

open access: yesCell Transplantation, 2015
Mesenchymal stem cells (MSCs) are immune privileged and a cell source for tissue repair. Previous studies showed that there is systemic mobilization of osteoblastic precursors to the fracture site.
Shuo Huang   +4 more
doaj   +1 more source

The Topological Properties of Stimuli Influence Fear Generalization and Extinction in Humans

open access: yesFrontiers in Psychology, 2018
Fear generalization is an etiologically significant indicator of anxiety disorders, and understanding how to inhibit it is important in their treatment.
Liang Xu   +16 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Compact, AGN-hosting Dwarf Galaxies with “Little Red Dot”-like SEDs in the Local Universe

open access: yesThe Astrophysical Journal
Local active galactic nuclei (AGNs) in dwarf galaxies are often considered as analogs for the earliest supermassive black holes, although their connections require more comprehensive examinations.
Lulu Bao   +3 more
doaj   +1 more source

Altered functional network topology properties to detect anxiety and depression caused by Crohn’s disease and disease severity

open access: yesBrain Research Bulletin
Objective: Here we investigated changes in topological properties of functional brain networks among individuals with Crohn’s disease (CD) and to determine whether these changes are related to CD severity, as well as CD-associated anxiety and depression,
Jiaxing Yang   +7 more
doaj   +1 more source

Learning Local Structured Correlation Filters for Visual Tracking via Spatial Joint Regularization

open access: yesIEEE Access, 2019
Robust visual tracking is a fundamental problem in the field of computer vision and has a wide range of practical applications. Recent progress in developing robust tracking methods are mainly made upon discriminative correlation filters (DCF).
Chenggang Guo, Dongyi Chen, Zhiqi Huang
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Biomechanical Analysis of Antibiotic-Treated Tendon Grafts With Digital Image Correlation: A Comparison Between Vancomycin, Gentamycin, and Tobramycin Soaking Techniques

open access: yesOrthopaedic Journal of Sports Medicine
Background: Previous research has shown that tendon graft soaking in vancomycin or tobramycin solution has no negative effects on graft mechanical properties, but there are no studies that have investigated graft mechanical properties after soaking ...
Michael Burton BS   +8 more
doaj   +1 more source

Construction and Analysis of Functional Networks in the Gut Microbiome of Type 2 Diabetes Patients

open access: yesGenomics, Proteomics & Bioinformatics, 2016
Although networks of microbial species have been widely used in the analysis of 16S rRNA sequencing data of a microbiome, the construction and analysis of a complete microbial gene network are in general problematic because of the large number of ...
Lianshuo Li   +5 more
doaj   +1 more source

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