Results 71 to 80 of about 6,232,235 (294)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Guidelines on sustainable mobility : shared transport [PDF]
, 2023 This is the fourth published guideline document, in a series of documents which are being published under the Resident First project headed by the Local Councils’ Association (LCA) and endorsed by all Local Councils in Malta and Gozo.
Zammit, Antoine +1 more
core
, 2022 RINGS is an international initiative to facilitate collaborative international effort to map all Antarctic ice-sheet margin to accurately estimate ice discharge from Antarcitca.
RINGS Action Group
core +1 more source
On the Genus of the Co-Annihilating Graph of Commutative Rings
Discussiones Mathematicae - General Algebra and Applications, 2019 Let R be a commutative ring with identity and 𝒰R be the set of all nonzero non-units of R. The co-annihilating graph of R, denoted by 𝒞𝒜R, is a graph with vertex set 𝒰R and two vertices x and y are adjacent whenever ann(x) ∩ ann(y) = (0).
Selvakumar K., Karthik S.
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Normality in group rings [PDF]
, 2008 Let KG be the group ring of a group G over a commutative ring K with unity. The rings KG are described for which xx(sigma)=x(sigma)x for all x=∑(g∈G)alfa(g)g∈KG, where x↦x(sigma)=∑(g∈G)alfa(g)f(g)sigma(g) is an involution of KG; here f:G→U(K) is a ...
Bódi, Viktor, Siciliano, S.
core +1 more source
The Computational Complexity of Subclasses of Semiperfect Rings
MathematicsThis paper studies the computational complexity of subclasses of semiperfect rings from the perspective of computability theory. A ring is semiperfect if the identity can be expressed as a sum of mutually orthogonal local idempotents.
Huishan Wu
doaj +1 more source
When is a regular local ring a locality?
Journal of Algebra, 1988 The author proves constructively and clearly the following nice fact: A normal local domain \((A,M)\) containing a field \(K\) is essentially of finite type over \(K\) if and only if: (1) the residue field \(A/M\) is a finitely generated extension of \(K\); (3) the quotient field \(L\) of \(A\) is a finitely generated extension of \(K\); and (2) \(\dim(
openaire +1 more source