Results 91 to 100 of about 6,232,235 (294)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
PLoS ONE, 2016 Provenance studies are an increasingly important analog for understanding how trees adapted to particular climatic conditions might respond to climate change. Dendrochronological analysis can illuminate differences among trees from different seed sources
Caroline Leland +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
On local Galois deformation rings: generalised reductive groups
Forum of Mathematics, PiWe study deformation theory of mod p Galois representations of p-adic fields with values in generalised reductive group schemes, such as L-groups and C-groups.
Vytautas Paškūnas, Julian Quast
doaj +1 more source
Coefficient subrings of certain local rings with prime-power characteristic
International Journal of Mathematics and Mathematical Sciences, 1995 If R is a local ring whose radical J(R) is nilpotent and R/J(R) is a commutative field which is algebraic over GF(p), then R has at least one subring S such that S=∪i=1∞Si, where each Si, is isomorphic to a Galois ring and S/J(S) is naturally isomorphic ...
Takao Sumiyama
doaj +1 more source
Journal of Pure and Applied Algebra, 2012 24 pages with a few corrections and minor ...
openaire +2 more sources
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Formal Groups and Hopf Algebras over Discrete Rings [PDF]
, 1974 A theory of formal schemes and groups over abitrary rings is presented. The flat formal schemes in this theory have coalgebras of distributions which behave in the usual way. Frobenius and Verschiebung maps are studied.
Robert A. Morris +3 more
core +1 more source
A survey of s-unital and locally unital rings
Revista Integración, 2019 We gather some classical results and examples that show strict inclusion between the families of unital rings, rings with enough idempotents, rings with sets of local units, locally unital rings, s-unital rings and idempotent rings.
Patrik Nystedt
doaj
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source