Local Stability of McKean-Vlasov Equations Arising from Heterogeneous Gibbs Systems Using Limit of Relative Entropies. [PDF]
Entropy (Basel), 2021 Dawson DA, Sid-Ali A, Zhao YQ.
europepmc +1 more source
Upravljavska sposobnost lokalnih samoupravnih skupnosti [PDF]
, 2015 Local communities have an important role in society. According to states legislature they execute local public policies. Those processes include local democracy, public administration, local economy and social entities.
Rožen, Tomaž
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The local stability of a modified multi-strain SIR model for emerging viral strains. [PDF]
PLoS One, 2020 Fudolig M, Howard R.
europepmc +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Spectral properties of non-local uniformly-elliptic operators [PDF]
, 2006 In this paper we consider the spectral properties of a class of non-local uniformly elliptic operators, which arise from the study of non-local uniformly elliptic partial differential equations. Such equations arise naturally in the study of a variety of
Niall Dodds +3 more
core
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Primal–Dual Stability in Local Optimality
Journal of Optimization Theory and ApplicationsMuch is known about when a locally optimal solution depends in a single-valued Lipschitz continuous way on the problem's parameters, including tilt perturbations. Much less is known, however, about when that solution and a uniquely determined multiplier vector associated with it exhibit that dependence as a primal-dual pair.
Matús Benko, R. Tyrrell Rockafellar
openaire +3 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Sleep orchestrates indices of local plasticity and global network stability in the human cortex.
, 2019 Animals and humans spend on average one third of their lives in sleep, but its functions remain to be specified. Distinct lines of research propose that sleep promotes local strengthening of information-bearing synapses (plasticity) and global ...
Spiegelhalder, Kai +12 more
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