Results 61 to 70 of about 806,523 (257)

Stability of the Replicator Equation for a Single-Species with a Multi-Dimensional Continuous Trait Space [PDF]

open access: yes
The replicator equation model for the evolution of individual behaviors in a single-species with a multi-dimensional continuous trait space is developed as a dynamics on the set of probability measures.
Frank Riedel   +2 more
core  

Summary of Ohio's Temporary Assistance to Needy Families Program; TANF Program report; Reinvesting in Ohio's families; Investing in Ohio's families

open access: yes, 2002
Annual; State fiscal year 2002-State fiscal year 2003.; "Prepared by The Ohio Department of Job and Family Services, Office of Family Stability in cooperation with The Institute for Local Government Administration and Rural Development at Ohio University'

core   +1 more source

The search for stability through stabilisation: case studies from Afghanistan and Nepal [PDF]

open access: yes, 2013
© Cranfield UniversityThis thesis focuses on what stability is, and what interventions have supported stability in four communities in Afghanistan and Nepal.
Dennys, C
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Local stability properties of complex, species-rich soil food webs with functional block structure. [PDF]

open access: yesEcol Evol, 2021
de Castro F   +18 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

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