Results 61 to 70 of about 3,086 (250)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

THE CHARACTERISTICS OF THE BUDGET PROCESS AT THE LEVEL OF THE LOCAL PUBLIC ADMINISTRATION IN THE RURAL SECTOR [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2013
The financial decentralization is an essential component part for the political, administrative and economic decentralization process, with major involvement on the economic and social system in Romania.
Daniela CRETU
doaj  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Local government financing in oromia regional administrations: particular to city administrations

open access: yes, 2019
The objective of this paper is to examine the revenue rights and expenditure obligations of local governments particularly city administrations. The paper has utilized the qualitative method in describing and analyzing the revenue rights and expenditure ...
Feyissa Tolessa
core  

Les administrations publiques locales dans le modèle "Administrations"

open access: yes, 1980
Local government administrations in the «Administrations» model by F. Péronnet. France's local government administrations («Administrations publiques locales» or «Apul») comprise an aggregate of administrations of territorial competence and essentially ...
Péronnet, François
core   +1 more source

Local Management and New Public Management

open access: yesCentral European Public Administration Review, 2011
Economic globalization, growingly differentiated and unstable markets, fiscal crises in light of increasing public expenditure are the elements of an uncertain future for local communities.
Irena Bačlija
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The Dilemma of Financial Autonomy in the Management of Public Finances at the Level of Local Governments [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2023
This research analyzes a group of municipalities in Algeria from the perspective of financial autonomy in the management of public finances at the level of local administrations.
Mohamed Mouloud Belaid   +2 more
doaj  

Challenges of Local Government Administration in Edo State of Ngieria

open access: yesLwati: A Journal of Contemporary Research, 2008
This paper examined the fundamental problems that envelope local government administration in Edo State, and discovered that the challenges are constitutional issues. It also identified problems of graft, poor revenue generation by local authorities, and poor revenue allocation cum fiscal transfer to local governments.
Azelama, JU, Oviasuyi, PO, Alimi, MK
openaire   +3 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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