Results 71 to 80 of about 3,086 (250)

AN ANALYSIS ON LOCAL ADMINISTRATIONS PROGRAMS IN TURKEY

open access: yes, 2017
Nowadays, presenting local public services and the importance of local governments providing public services within public administration organization is gradually increasing.
KAVİLİ ARAP, SULTAN, YÜCEBAŞ, ELİF
core  

CONSIDERAŢII ASUPRA REGLEMENTĂRILOR PRIVIND AUTONOMIA LOCALĂ IN BASARABIA SUB REGIMUL ŢARIST-RUSESC

open access: yesStudia Universitatis Moldaviae: Stiinte Sociale, 2007
The system that was based on „zemstvo”, applied at the time of „tzarism” had on its foundation on a very well pronounced autonomy, that was looking for administrations, interested in the needs of local character, to concentrate the attention on local ...
USM ADMIN
doaj  

Book Review: "From the War on Poverty to the War on Crime: The Making of Mass Incarceration in America"

open access: yesQuarterly Journal of Austrian Economics, 2020
The great extent of federal involvement in local criminal justice matters was not established overnight, but over the course of several decades. This is the primary subject of Elizabeth Hinton’s book, _From the War on Poverty to the War on Crime: The ...
Tate Fegley
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Solutions applicable by local administrations for urban logistics improvement

open access: yes, 2020
This paper aims to establish a compilation of the solutions or initiatives that can be implemented by local administrations in order to improve freight deliveries in urban environments.
Juan Larrañ   +3 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

ASSESSMENT OF THE LOCAL STATE ADMINISTRATION PREPAREDNESS LEVEL ON THE SOLUTION OF CRISIS EVENTS

open access: yesCBU International Conference Proceedings, 2019
The preparedness of the state and local administration to deal with different crisis events is a prerequisite for a functioning crisis management system in each country. However, the level of preparedness varies across the state from region to region, which can be caused by various factors.
Daniel Brezina, Michal Titko
openaire   +3 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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