Results 91 to 100 of about 3,086 (250)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Legal regulation of the activities of local executive government bodies

, 2023
Назар Т.Я. Правове регулювання діяльності місцевих органів виконавчої влади / Тетяна Ярославівна Назар // Економіка. Фінанси. Право. - 2023. - № 4. - С.
ORCID ID:, Назар, Т.Я., Nazar, T.Ya.   +2 more
core  

Relația interes public–proces decizional–modernizarea administrației publice locale în unele țări din spațiul ex-sovietic

Revista Transilvană de Ştiinţe Administrative, 2021
The article contains a detailed analysis of the relational aspects of the public interest and deci­sion-making, modernization of local public adminis­tration in some post-Soviet countries.
Victor Saca, Tatiana Bogos
doaj  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

The impact of ICT on local administrations in Italy: state of the art, swot analysis and improvement solutions

, 2007
Local administrations in Italy are involved, since the beginning of the 1990s, in a large and deep process of reform. This reform aims at their modernization and basically at enhancing their efficiency and effectiveness.
FONTANA, FEDERICO
core  

Elasticities of Regional and Local Administrations Expenditures - the Portuguese case [PDF]

This work analyses the evolution of real public expenditures of local and regional administrations (LRA), in Portugsl, in the period after the Second World War. It also aims to estimate the elasticities associated to determinants, which explain the found
Paulo Reis Mourão
core   +2 more sources

ROLA I MIEJSCE ADMINISTRACJI SPRAW WEWNĘTRZNYCH W SYSTEMIE WŁADZY PAŃSTWOWEJ II RZECZYPOSPOLITEJ

Zeszyty Prawnicze, 2016
ROLE THE INTERNAL AFFAIRS ADMINISTRATION WITHIN THE GOVERNMENT THE IN POLISH SECOND REPUBLIC Summary Basic and primary functions of administration were peacekeeping and regulatory activity.
Andrzej Misiuk
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

The impact of ICT on local administrations in Italy: state of the art, swot analysis and improvement solutions

, 2006
Local administrations in Italy are involved, since the beginning of the 1990s, in a large and deep process of reform. This reform aims at their modernization and basically at enhancing their efficiency and effectiveness.
FONTANA, FEDERICO
core  

Cooperation between decentralized and devolved administrations in France. Contribution to the study of relations between the State and local authorities

, 2023
Le rapprochement des administrations déconcentrées et décentralisées en France est une question qui se pose aujourd'hui. Lesexplications en sont multiples mais d'abord d'ordre budgétaire.
Ali Mahaman Dan Kano, Mansour
core