Results 41 to 50 of about 1,152,277 (267)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser +5 more
wiley +1 more source
THE ROLE OF LOCAL ACTIVITY GROUPS IN SOCIAL AND ECONOMIC DEVELOPMENT COMMUNES
Research on Enterprise in Modern Economy Theory and Practice, 2013 Polish accession to the European Union has set many challenges facing the country in a variety of ways: social, economic and political. It created a chance of getting financial support for rural development.
Katarzyna Szymańska
doaj
Cadernos EBAPE.BREste artigo descreve e analisa o processo de formação e desenvolvimento do Pólo Moveleiro de Lucas do Rio Verde (MT), a partir de um estudo histórico-biográfico de um conjunto de pequenas e médias empresas que buscaram na parceria e na ação associativa a
Jorge Oneide Sausen +1 more
doaj +1 more source
Features innovative environmental management strategies of local development
Ученые записки Российской академии предпринимательства, 2021 The article defines the importance of the formation and development of innovative environmental management, the basic strategy of innovation management, identified the main components of innovative environment of management in modern conditions of ...
O. B. Repkina
doaj
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
BuildingsThis research is focused on housing stock rehabilitation and construction in Urban Rehabilitation Areas located in diverse contexts in the Portuguese territory.
Cilisia Ornelas +2 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Environmental Research Letters, 2022 Understanding the motivation to adopt personal household adaptation behaviors in the face of climate change-related hazards is essential for developing and implementing behaviorally realistic interventions that promote well-being and health.
Gabrielle Wong-Parodi, Dana Rose Garfin
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source