Results 51 to 60 of about 1,270,152 (266)

A constituição do Pólo Moveleiro de Lucas do Rio Verde (MT): uma retrospectiva histórica de uma iniciativa coletiva de desenvolvimento local e regional

open access: yesCadernos EBAPE.BR
Este artigo descreve e analisa o processo de formação e desenvolvimento do Pólo Moveleiro de Lucas do Rio Verde (MT), a partir de um estudo histórico-biográfico de um conjunto de pequenas e médias empresas que buscaram na parceria e na ação associativa a
Jorge Oneide Sausen   +1 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Pro-ecological initiatives in the development strategies of manufacturing companies

open access: yesEconomics and Environment
Academics and practitioners have already acknowledged the importance of pro-ecological initiatives in order to meet societal expectations and, in the process, gain a competitive advantage over market rivals.
Jacek Wysocki   +1 more
doaj   +1 more source

Features innovative environmental management strategies of local development

open access: yesУченые записки Российской академии предпринимательства, 2021
The article defines the importance of the formation and development of innovative environmental management, the basic strategy of innovation management, identified the main components of innovative environment of management in modern conditions of ...
O. B. Repkina
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Evolution of local adaptations in dispersal strategies [PDF]

open access: yesOikos, 2006
The optimal probability and distance of dispersal largely depend on the risk to end up in unsuitable habitat. This risk is highest close to the habitat's edge and consequently, optimal dispersal probability and distance should decline towards the habitat's border. This selection should lead to the emergence of spatial gradients in dispersal strategies.
Gros, Andreas   +2 more
openaire   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Housing in Urban Rehabilitation Areas: Opportunities for Local Management in Housing Provision and Preservation

open access: yesBuildings
This research is focused on housing stock rehabilitation and construction in Urban Rehabilitation Areas located in diverse contexts in the Portuguese territory.
Cilisia Ornelas   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

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