Results 81 to 90 of about 1,270,152 (266)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Strategi Pengembangan UMKM Berbasis Potensi Lokal Melalui Penerapan Digitalisasi Kewirausahaan
LamahuThe low use of digital technology by Micro, Small, and Medium Enterprises (MSMEs) based on local potential is still an obstacle in increasing competitiveness and business sustainability in the midst of digital economy transformation.
Nur Fahmi Ahmad +5 more
doaj +1 more source
BMC Public Health, 2018 Background The decline in global malaria cases is attributed to intensified utilization of primary vector control interventions and artemisinin-based combination therapies (ACTs). These strategies are inadequate in many rural areas, thus adopting locally
Jacinter A. Amadi +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Indonesian Journal of Innovation and Applied SciencesThis research aims to obtain in-depth information about the quality of Conical Hat production (Caping) of the women's group of Conical Hat craftsmen is still low compared to the same production in the market, and the market share of Conical Hat ...
Adi Sumandiyar
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Financial Strategies for the Romanian Local Public Administration
Transylvanian Review of Administrative Sciences, 2011 Public administration reform at all governmental levels constitutes an important component of the transformation process from a centralized system to democratic governance. This process involved important legislative and institutional changes in order to
Attila GYÖRGY +2 more
doaj
Local strategies for development [PDF]
, 2010 In the current Cuban context the local level is coming to be considered crucial for the development of the country, resulting in the deployment of existing capacities to municipal level and a more efficient and effective management. This requires methods that can integrate institutional decisions – currently fragmented and top-down – according to needs
openaire
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source