Results 111 to 120 of about 519,807 (275)

Fare Mente Locale [PDF]

open access: yes, 2013
“Fare Mente Locale” Pratiche di sviluppo locale autosostenibile nella comunità di Piazza al Serchio a cura di Bonini Daniele Il lavoro da me ipotizzato per la tesi di laurea specialistica in scienze sociali (89\s) riguarda nello specifico la sociologia ...
BONINI, DANIELE
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Quando il risultato elettorale è scontato… Il ruolo dei quotidiani locali durante le elezioni regionali del 2010 in Umbria

open access: yesQOE-IJES, 2011
Gli scontri nel PD umbro e il ruolo della stampa locale Il ruolo delle primarie nella selezione del candidato del PD Modalità di conduzione della ricerca I temi trattati dalla stampa locale Gli attori protagonisti nella stampa locale umbra
Antonio Ciaglia, Marco Mazzoni
doaj   +1 more source

Local Homology and Local Cohomology

open access: yes, 2004
Let $(R, {\frak m})$ be a local ring, $I$ a proper ideal of $R$ and $M$ a finitely generated $R$-module of dimension $d$. We discuss the local homology modules of $H^d_I(M)$. When $M$ is Cohen-Macaulay, it is proved that $H^d_{\frak m}(M)$ is co-Cohen-Macaulay of N.dimension $d$ and $H^{\underline{x}}_d(H^d_{\frak m}(M))\cong\hat{M}$ where $\underline ...
openaire   +3 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

The 2007 National School Climate Survey: The Experiences of Lesbian, Gay, Bisexual and Transgender Youth in Our Nation's Schools [PDF]

open access: yes, 2008
GLSEN's National School Climate Survey is the only national survey to document the experiences of students who identify as lesbian, gay, bisexual and transgender (LGBT) in America's secondary schools.
Elizabeth M. Diaz   +2 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy