Results 81 to 90 of about 92,788 (267)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Localisation of the unerupted maxillary canine
Australasian Orthodontic Journal, 1986 The need to localise unerupted teeth is a common clinical problem. lnspection, palpation and radiographic views are discussed. This paper concentrates on the radiographic localisation of the unerupted maxillary canine.
Jacobs Stanley G.
doaj +1 more source
Noisy localisation on the sphere
International Journal of Intelligent Defence Support Systems, 2011 Localisation is a vital problem in a multitude of research fields, such as navigation, tracking, sensor networks and so on. In previous work, the problem is considered in the plane or in three-dimensional space. This work deals with the problem of distance-based localisation on the surface of the earth when the points lie in a two-dimensional manifold.
Yu, Changbin (Brad) +3 more
openaire +3 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Remote SensingIn this study, the full-focusing (FF) algorithm is reviewed with the objective of optimizing it for processing data from different types of surfaces probed in altimetry.
Samira Amraoui +9 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Journal of Neurology, Neurosurgery & Psychiatry, 2003 Neurological signs have been described as "false localising" if they reflect dysfunction distant or remote from the expected anatomical locus of pathology, hence challenging the traditional clinicoanatomical correlation paradigm on which neurological examination is based.
openaire +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source