Results 161 to 170 of about 1,706,702 (287)

Microplastics in the Female Genital Tract and Fetoplacental Continuum: A Lesion-Based Framework for Pathophysiological Interpretation. [PDF]

Pathophysiology
Das SK, Karak P, Parveen A, Das SN, Nerune SM.   +4 more
europepmc   +1 more source

State Contracting Standards Board

, 2013
Updated irregularly; Began in 2006?; Title from home page (publisher's Web site, viewed Nov. 7, 2011).; At head of title: State of Connecticut.; Official website of the Connecticut State Contracting Standards Board.

core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Clinical application of artificial intelligence technology in epilepsy. [PDF]

Acta Epileptol
Ren Q, Zhang Y, Deng X, Fu M, Li X, Wang L, Chen X, Yang Y, Zhang J.   +8 more
europepmc   +1 more source

State Contracting Standards Board

, 2017
Updated irregularly; Began in 2006?; Title from home page (publisher's Web site, viewed Nov. 7, 2011).; At head of title: State of Connecticut.; Official website of the Connecticut State Contracting Standards Board.

core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Adopting Standards Based XML file formats in Open Source Localisation

, 2005
Frimannsson, Asgeir, Hogan, James M.
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Comparing intraoperative ultrasound and wire-guided localisation for skin cancer metastases: impacts on patient safety, outcomes, costs, and implementation. [PDF]

World J Surg Oncol
Hawwash N, Royle G, Mullan D, Kosutic D, Gajanan K.   +4 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source