Results 161 to 170 of about 1,518,582 (299)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Localized Microscale Electrochemistry on a Monolithic Electrode: An Electrochemical Microarray Chip [PDF]

, 2009
Geun‐Cheol Gil, Seung-Woo Lee, Gaurav Pratap Singh, Ravi F. Saraf   +3 more
openalex   +1 more source

RNA localization [PDF]

Journal of Cell Science, 2005
Yaron, Shav-Tal, Robert H, Singer
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

In situ subcellular localization of epitope‐tagged human and rabbit carboxylesterases [PDF]

, 1998
Philip M. Potter, Judith S. Wolverton, Christopher L. Morton, David O. Whipple, Mary K. Danks   +4 more
openalex   +1 more source

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy

, 2021
Bing-Ru Yan, Taoyingnan Li, Étienne Coyaud, Estelle Laurent, Jonathan St‐Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell   +8 more
openalex   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Feasibility and Safety of CIOS Spin for One-Stop Pulmonary Nodule Localization and Resection. [PDF]

Interdiscip Cardiovasc Thorac Surg
Liu Y, Ma H, Yu X, Wang N.
europepmc   +1 more source

Interictal and postictal 18F-FDG PET/CT in epileptogenic zone localization

, 2022
Marcela Santos Carvalho, Marina K. M. Alvim, Elba Etchebehere, Allan O. Santos, Celso Darío Ramos, Juliana Luz Passos Argenton, Fernando Cendes, Bárbara Juarez Amorim   +7 more
openalex   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source