Results 181 to 190 of about 1,518,582 (299)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Erratum: Pilot Study: Precision in Plastic Surgery: Efficacy of Nerve Mapping and Neural Stimulation for Facial Nerve Localization in Permanent Filler Removal-Erratum. [PDF]

Plast Reconstr Surg Glob Open
Akkour M, Alyahya M, Alghamdi AM, Elbarqy R, Alawirdhi B.   +4 more
europepmc   +1 more source

Distance Measurement-Based Cooperative Source Localization: A Convex Range-Free Approach

, 2013
Fatma Kiraz
openalex   +1 more source

FLACK: Counterexample-Guided Fault Localization for Alloy Models

, 2020
Guolong Zheng
openalex   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Comparison of Two Dye Marking Methods for Preoperative Localization of Pulmonary Nodules Guided by Electromagnetic Navigation Bronchoscopy. [PDF]

Thorac Cancer
Yang H, Luo KJ, Liang Y, Lin XD, Yang H, Xie JW, Wang GM, Yuan L, Zhao ZR, Su XD, Hu Y, Zhang LJ, Yang HX, Lin YB.   +13 more
europepmc   +1 more source

Author response: The non-mitotic role of HMMR in regulating the localization of TPX2 and the dynamics of microtubules in neurons

Yi‐Ru Chen, Shun-Cheng Tseng, Peng-Tzu Chen, Eric Hwang   +3 more
openalex   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Transformation of localized states of relativistic hydrogen atom into two-component form

, 2016
Tomasz M. Rusin
openalex   +1 more source