ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source
Dynamical analysis and soliton solutions to (3+1)-dimensional extended quantum nonlinear Zakharov-Kuznetsov equation. [PDF]
Fatima M +6 more
europepmc +1 more source
Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Volumetric Ablation of Phenolic Resin in Extreme Environments: A Variable-Property Physics-Informed Neural Network Framework. [PDF]
Du W, Ma T, Song H.
europepmc +1 more source
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera +20 more
wiley +1 more source
Solitons, bifurcation, chaos, and stability of the fractional Schrödinger-Hirota equation with beta derivative. [PDF]
Al Amin M +4 more
europepmc +1 more source
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch +5 more
wiley +1 more source
Preparation and Photophysical Study of Rhodamine-Perylenebisimide Electron Donor-Acceptor Dyad/Triads Containing Flexible Linkers. [PDF]
Guan X, Bai H, Zhao J, Wan Y.
europepmc +1 more source
Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park +5 more
wiley +1 more source
Analytical and numerical investigations, data-driven modeling via an analytical-machine learning approach, and chaotic analysis of a nonlinear fractional soliton neuron model. [PDF]
Amin MR, Akter R, Helal KM, Ullah MS.
europepmc +1 more source

