Results 171 to 180 of about 168,312,063 (201)

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

Soliton dynamics and stability in resonant nonlinear Schrödinger systems with cubic quintic effects via enhanced modified extended tanh function method. [PDF]

Sci Rep
Tarek A, Ahmed HM, Badra N, Samir I.
europepmc   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

Susceptibility to Pitting Corrosion of AerMet 100 and 4340 Alloys for Aeronautical Applications. [PDF]

Materials (Basel)
Huerta-Zavala MS, Gaona-Tiburcio C, Nieves-Mendoza D, Jaquez-Muñoz JM, Cabral-Miramontes J, Maldonado-Bandala E, Croche-Belin R, Baltazar-Zamora MA, Landa-Ruiz L, Lopez-Leon LD, Olguin-Coca J, Almeraya-Calderon F.   +11 more
europepmc   +1 more source

Copine‐4 Paraneoplastic Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Mimi S. Fang, Amy Ml Quek, Clement Yong, Amir Adeli, Gabrielle N. Conway, Connie E. Lesnick, Diana Anissian, Divyanshu Dubey, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael Gilligan, Andrew McKeon   +12 more
wiley   +1 more source

Multi-objective optimization of an energy-efficient diaphragm spring for clutch applications. [PDF]

Sci Rep
Baranovskyi D, Sergienko A, Kalinin P, Sergienko N, Vladov S, Gasanov M, Pavlova N, Tykhanovskyi V, Nazarov A, Hutsol T.   +9 more
europepmc   +1 more source

Proton Sharing in Polycarboxylic Acids in Aqueous Solution. [PDF]

JACS Au
Tomaník L, Tůma J, Öhrwall G, Golnak R, Le Nguyen NL, Credidio B, Kaur H, Slavíček P, Winter B, Schewe HC.   +9 more
europepmc   +1 more source

Bifurcation, quasi-periodic dynamics, chaos, and soliton waves in the van der Waals normal form for fluidized granular matter. [PDF]

Sci Rep
Alam MN, Haque MZ, Ahmed SF, Islam MN, Sim KS.   +4 more
europepmc   +1 more source

Hyperbranched Polyol Process for the Synthesis of Multifunctional Cobalt Nanocomposites: Interplay of Polymer Architecture, Metal Localization and Material Properties. [PDF]

Nanomaterials (Basel)
Kutyreva MP, Burmatova A, Khannanov A, Khaldeeva E, Kiiamov A, Batulin R, Evtugyn V, Emelianov D, Zubaidullina L, Ulakhovich NA.   +9 more
europepmc   +1 more source