Results 71 to 80 of about 42,506 (251)
The Localized Method of Fundamental Solution for Two Dimensional Signorini Problems
Computer Modeling in Engineering & Sciences, 2022 Zhuowan Fan +4 more
openaire +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Flow accelerated preferential weld corrosion of X65 steel in brine [PDF]
, 2014 Preferential weld corrosion (PWC) remains a major operational challenge that jeopardizes the integrity of oil and gas production facilities. It is the selective dissolution of metal associated with welds, such that the weld metal (WM) and / or the ...
Adegbite, Michael Adedokun
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Dielectrophoresis-Driven Spreading of Immersed Liquid Droplets [PDF]
, 2015 In recent years electrowetting-on-dielectric (EWOD) has become an effective tool to control partial wetting. EWOD uses the liquid−solid interface as part of a capacitive structure that allows capacitive and interfacial energies to adjust by changes in ...
Christophe L. Trabi +8 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Electrolytic purification of water [PDF]
, 2006 This thesis develops the concept of an in situ electrolytic processor, a machine with electrochemical functions that purifies aqueous fluids at the point of production, whether from a bore water supply or effluent from a tannery.
Mathieson, Grant Alexander
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The force coupling method: A flexible approach for the simulation of particulate flows [PDF]
, 2009 We describe the basis of the Force Coupling Method. The flow disturbance induced by each particle in a suspension is represented by a low order multipole expansion.
Maxey, Martin R., Climent, Éric
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