Familial localized scleroderma with paediatric onset: a review. [PDF]
Postepy Dermatol Alergol, 2021 Localized scleroderma is an inflammatory disease causing sclerosis of the skin. The aetiology and pathogenesis of localized scleroderma remain unclear. Localized scleroderma is considered a genetically driven disease. It is not well understood if genetic
Yurtsever I +5 more
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Single-Cell Transcriptome Analysis Identifies Subclusters with Inflammatory Fibroblast Responses in Localized Scleroderma. [PDF]
Int J Mol Sci, 2023 Localized scleroderma (LS) is an autoimmune disease with both inflammatory and fibrotic components causing an abnormal deposition of collagen in the skin and underlying tissue, often leading to disfigurement and disability. Much of its pathophysiology is
Werner G +7 more
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Fat graft and platelet-rich plasma treatment for localized facial scleroderma
Turkish Journal of Plastic Surgery, 2021 Scleroderma is an autoimmune disorder characterized by hardening of the skin on the hands, arms, and face. Immunosuppressors, vasodilators, and physiotherapy are among the treatments for scleroderma. Although these treatments can improve quality of life,
Ali Gokkaya +5 more
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SAGE Open Medical Case Reports, 2021 The en coup de sabre variant of linear scleroderma typically occurs in children. We report a unique case of adult-onset en coup de sabre scleroderma in a patient with linear localized scleroderma profunda.
Roxana Mititelu +3 more
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Revealing Microvascular Involvement in Pediatric Localized Scleroderma Through Nailfold Capillaroscopy [PDF]
ChildrenBackground/Objectives: Juvenile localized scleroderma (jLoS) is a chronic inflammatory disorder with skin and subcutaneous tissue involvement. Microvascular alterations are thought to contribute to its pathogenesis.
Sema Nur Taşkın +5 more
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Study about evaluation of efficacy of methotrexate in localized scleroderma using ultrasonography. [PDF]
Skin Res Technol, 2023 Zhang F, Li J, Zhao Q, Liu H, Zhang F.
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Immunopathogenesis of Pediatric Localized Scleroderma
Frontiers in Immunology, 2019 Localized scleroderma (LS) is a complex disease characterized by a mixture of inflammation and fibrosis of the skin that, especially in the pediatric population, also affects extracutaneous tissues ranging from muscle to the central nervous system ...
Kathryn S. Torok +11 more
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Cross‐sectional quantitative validation of the paediatric Localized Scleroderma Quality of Life Instrument (
Journal of the European Academy of Dermatology and Venereology, 2023 The Localized Scleroderma Quality of Life Instrument (LoSQI) is a disease‐specific patient‐reported outcome (PRO) measure designed for children and adolescents with localized scleroderma (LS; morphea).
Christina K. Zigler +10 more
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Hyaluronic Acid Filler Injection for Localized Scleroderma - Case Report and Review of Literature on Filler Injections for Localized Scleroderma. [PDF]
Clin Cosmet Investig Dermatol, 2022 Introduction Localized scleroderma, also known as Morphea, is a chronic inflammatory condition of connective tissue, the etiology of which is unknown. There is skin thickening with increased quantities of collagen in the indurative lesion. Skin hyperemia
Sharad J.
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