Results 51 to 60 of about 14,557 (255)
PPAR? Downregulation by TGF in Fibroblast and Impaired Expression and Function in Systemic Sclerosis: A Novel Mechanism for Progressive Fibrogenesis [PDF]
, 2010 The nuclear orphan receptor peroxisome proliferator-activated receptor-gamma (PPAR-γ) is expressed in multiple cell types in addition to adipocytes. Upon its activation by natural ligands such as fatty acids and eicosanoids, or by synthetic agonists such
A Galli +75 more
core +4 more sources
Frequency of occurrenceof tumor-associated localized scleroderma
Лечащий ВрачBackground. Tumor-associated localized scleroderma is observed among patients with localized scleroderma. It is assumed that the development of this condition may be facilitated by both the inflammatory processes in scleroderma and oncological processes ...
P. O. Kazakova
doaj +1 more source
Zdorovʹe Rebenka, 2019 Among rheumatic diseases in children, a special place belongs to juvenile localized scleroderma, which is highlighted as a separate form in the structure of scleroderma diseases and is characterized by: the onset of the disease up to 16 years, skin ...
L.F. Bogmat, V.V. Nikonova
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SAGE Open Medical Case Reports, 2021 The en coup de sabre variant of linear scleroderma typically occurs in children. We report a unique case of adult-onset en coup de sabre scleroderma in a patient with linear localized scleroderma profunda.
Roxana Mititelu +3 more
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The lens as a model for fibrotic disease [PDF]
, 2011 Fibrosis affects multiple organs and is associated with hyperproliferation, cell transdifferentiation, matrix modification and contraction. It is therefore essential to discover the key drivers of fibrotic events, which in turn will facilitate the ...
Dawes, LJ, Eldred, JA, Wormstone, IM
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Fat graft and platelet-rich plasma treatment for localized facial scleroderma
Turkish Journal of Plastic Surgery, 2021 Scleroderma is an autoimmune disorder characterized by hardening of the skin on the hands, arms, and face. Immunosuppressors, vasodilators, and physiotherapy are among the treatments for scleroderma. Although these treatments can improve quality of life,
Ali Gokkaya +5 more
doaj +1 more source
Nailfold capillaroscopy in children and adolescents with rheumatic diseases [PDF]
, 2012 OBJECTIVE: To assess nailfold capillaroscopy in children and adolescents with autoimmune rheumatic diseases (juvenile idiopathic arthritis, systemic lupus erythematosus, juvenile dermatomyositis, scleroderma and mixed connective tissue disease) and ...
Hilário, Maria Odete Esteves +3 more
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Modern methods of a localized scleroderma diagnostics [PDF]
Саратовский научно-медицинский журнал, 2016 Localized scleroderma (LS) is a disease that is characterized by the appearance of inflammatory, sclerotic and/or atrophic changes in the affected areas of the skin and underlying tissues.
Moiseyev А.А., Utz S.R.
doaj
Ultrasonographic evaluation of submucosal thickness in oral submucous fibrosis patients : a cross-sectional study [PDF]
, 2018 Purpose: To evaluate the role of ultrasonography in oral submucous fibrosis (OSMF) patients. Material and methods: A total of 150 subjects were divided equally into six groups (Group I: 25 healthy subjects; Group II: 25 healthy subjects with habit; Group
Dhole, Apeksha, Dupare, Aditya
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The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
Advanced Science, EarlyView.This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen +6 more
wiley +1 more source