Results 81 to 90 of about 9,982 (193)

Immunotherapy‐Related Cutaneous Toxicities in Melanoma: A Dermoscopic Perspective

open access: yesJEADV Clinical Practice, Volume 5, Issue 2, Page 402-414, June 2026.
Dermoscopy serves as a valuable tool in the everyday dermatological and oncological practice for melanoma patients, allowing for the prompt identification of immune‐related cutaneous toxicities and guiding clinicians toward appropriate therapeutic decisions.
Grażyna Kamińska‐Winciorek   +3 more
wiley   +1 more source

Ribosomal Proteins in Cell Biology and Cancer

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
The functions of ribosomal proteins (RPs) extend beyond the conventional translation process, as they also regulate gene expression, stress responses, and disease progression. Dysregulation of RPs contributes to the onset and progression of various diseases, including cancer and ribosomopathies, underscoring their dual role as critical disease ...
Ao Zhang   +4 more
wiley   +1 more source

Localized severe scleroderma: a retrospective study of 26 pediatric patients

open access: yes, 2010
Juvenile localized scleroderma includes different conditions characterized by skin hardening with increased collagen deposition. Although juvenile localized scleroderma is considered a relatively benign disease, lesions may extend through the dermis ...
M. Beltramelli   +9 more
core   +1 more source

Internal Involvement in Localized Scleroderma

open access: yesMedicine, 1994
We studied 76 consecutive patients with localized scleroderma (morphea with or without linear scleroderma) and analyzed the frequency, prognosis, and predictors of internal involvement in a subset of 53 patients systematically investigated for the presence of such involvement.
L, Dehen   +3 more
openaire   +2 more sources

No Evidence for Borrelia burgdorferi-Specific DNA in Lesions of Localized Scleroderma

open access: yes, 1995
A possible association of Borrelia burgdorferi with localized scleroderma is currently the focus of intense research and discussion. Skin biopsies from 30 patients with localized scleroderma (28 of the plaque type/morphea; two linear scleroderma) were ...
Meurer, Michael   +5 more
core   +1 more source

Recent Advances in Localized Scleroderma

open access: yesSclerosis
Localized scleroderma (LSc), or morphea, is an autoimmune connective tissue disease causing inflammation and fibrosis of the skin and underlying tissues. While distinct from systemic sclerosis, its clinical presentation is highly diverse.
Toshiya Takahashi   +2 more
doaj   +1 more source

Psychometric properties of the Children’s Dermatology Life Quality Index in pediatric localized scleroderma

open access: yes, 2018
Introduction: The Children’s Dermatology Life Quality Index has been used to measure quality of life in studies of pediatric localized scleroderma, which suggested only modest effects on quality of life.
Christina K Zigler   +4 more
core   +1 more source

Reliability of LoSCAT score for activity and tissue damage assessment in a large cohort of patients with Juvenile Localized Scleroderma

open access: yesPediatric Rheumatology Online Journal, 2018
Objectives To assess reliability of the two indexes of Localized Scleroderma Cutaneous Assessment Tool (LoSCAT), the modified Localized Scleroderma Skin Severity Index (mLoSSI) and the Localized Scleroderma Skin Damage Index (LoSDI), when applied by ...
Anna Agazzi   +4 more
doaj   +1 more source

Presentations and Treatment of Childhood Scleroderma: Localized Scleroderma, Eosinophilic Fasciitis, Systemic Sclerosis, and Graft-Versus-Host Disease

open access: yes, 2011
Juvenile scleroderma is a rare connective tissue disease that involves the skin and subcutaneous tissue. Among all presentations of juvenile scleroderma, localized scleroderma (JLSc) is the most frequent, followed by systemic disease (JSSc) and ...
Barbara Fiebig   +4 more
core   +1 more source

Novel Autoantibody to Cu/Zn Superoxide Dismutase in Patients with Localized Scleroderma

open access: yes, 2004
Abnormal production of reactive oxygen species (ROS) induces tissue damage and superoxide dismutase (SOD) that converts superoxide radicals to hydrogen peroxide functions as defense against ROS. Cu/Zn SOD administration has been shown to be effective for
Takehara, Kazuhiko   +7 more
core   +1 more source

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