Localized Scleroderma Cutaneous Assessment Tool (LoSCAT) adapted for use in adult patients: report from an initial validation study [PDF]
Health and Quality of Life Outcomes, 2018 Background Localized scleroderma (LoS) affects both children and adults and is associated with permanent functional and cosmetic impairment, and reduced quality of life predominating in adults. The Localized Scleroderma Cutaneous Assessment Tool (LoSCAT)
Alina Skrzypek-Salamon +3 more
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Reliability of LoSCAT score for activity and tissue damage assessment in a large cohort of patients with Juvenile Localized Scleroderma [PDF]
Pediatric Rheumatology Online Journal, 2018 Objectives To assess reliability of the two indexes of Localized Scleroderma Cutaneous Assessment Tool (LoSCAT), the modified Localized Scleroderma Skin Severity Index (mLoSSI) and the Localized Scleroderma Skin Damage Index (LoSDI), when applied by ...
Anna Agazzi +4 more
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Intramuscular Polydeoxyribonucleotides in Fibrotic and Atrophic Localized Scleroderma: An Explorative Prospective Cohort Study [PDF]
Biomedicines, 2023 Effective options in the quiescent, scantily inflammatory phase of localized scleroderma (morphea) are lacking. A cohort study in patients with histologically confirmed fibroatrophic morphea explored the therapeutic value of the anti-dystrophic A2A ...
Maurizio Romagnuolo +5 more
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Associations between Disease Activity/Severity and Damage and Health-Related Quality of Life in Adult Patients with Localized Scleroderma-A Comparison of LoSCAT and Visual Analogue Scales. [PDF]
J Clin Med, 2020 Localized scleroderma (LoS) is a chronic fibrosing disorder of the skin and, less commonly, subcutaneous tissues. As the disease causes subjective symptoms, cosmetic defects, and, at times, functional disability, subjects with LoS experience deterioration of their health-related quality of life (HRQoL).
Lis-Święty A +3 more
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Endpoints and outcomes for localized scleroderma/morphea: a scoping literature review [PDF]
Pediatric Rheumatology Online JournalBackground Current treatment for localized scleroderma (LS) has been shown to halt disease activity, but little is still known about patient experiences with these treatments, nor is there consensus about optimal measurement strategies for future ...
Alexy Hernandez +5 more
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Efficacy and Safety of Ablative Fractional Laser-Assisted Delivery of Methotrexate in Adults with Localized Scleroderma: A Randomized and Controlled Clinical Trial [PDF]
Pharmaceutics, 2022 Localized scleroderma (LS) is an autoimmune disease with sclerosis of the skin as the main manifestation. Currently, there is no specific treatment for LS.
Qing Guo +6 more
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Przegląd Dermatologiczny, 2017 Localized scleroderma is a rare autoimmune disorder affecting the dermis, subcutaneous tissue and deeper structures. The course of localized scleroderma includes three stages: early inflammation, progressive sclerosis and atrophy. The active stage of the
Katarzyna Wolska-Gawron +1 more
doaj +5 more sources
Is adiponectin involved in morphea pathogenesis? – first observational study [PDF]
Frontiers in ImmunologyBackgroundMorphea is a chronic inflammatory condition characterized by fibrosis of the skin and/or subcutaneous tissues. Adiponectin is an adipokine known for its anti-inflammatory and antifibrotic properties.
Adriana Polańska +5 more
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Health-related quality of life and its influencing factors in adult patients with localized scleroderma - a cross-sectional study [PDF]
Health and Quality of Life Outcomes, 2020 Background Localized Scleroderma (LoS) is an autoimmune connective tissue disease that affects skin and less commonly subcutaneous tissues. The illness occurs in children and adults, and may have a serious impact on health-related quality of life (HRQoL).
Anna Lis-Święty +3 more
doaj +2 more sources
Narrow-Band Reflectance Spectrophotometry for the Assessment of Erythematous and Hyperpigmented Skin Lesions in Localized Scleroderma: A Preliminary Study [PDF]
Clinical, Cosmetic and Investigational Dermatology, 2021 Michal Szczepanek, Aleksandra Frątczak, Anna Lis-Święty Department of Dermatology, School of Medicine in Katowice, Medical University of Silesia, Katowice, PolandCorrespondence: Anna Lis-ŚwiętyDepartment of Dermatology, School of Medicine in Katowice ...
Szczepanek M +2 more
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