Study about evaluation of efficacy of methotrexate in localized scleroderma using ultrasonography. [PDF]
Skin Res Technol, 2023 Abstract Background The treatment and curative effect evaluation of localized scleroderma (LS) still perplexes many clinical workers. Purpose To investigate the efficiacy of methotrexate in the treatment of LS by the evaluation of ultrasonography. Methods A prospective study enrolled 10 patients treated with MTX for at least 6 months was conducted ...
Zhang F, Li J, Zhao Q, Liu H, Zhang F.
europepmc +2 more sources
Clinical and laboratory characterization of patients with localized scleroderma and response to UVA-1 phototherapy: In vivo and in vitro skin models. [PDF]
Photodermatol Photoimmunol Photomed, 2022 Abstract Background/Purpose Localized scleroderma (LS) is a rare disease leading to progressive hardening and induration of the skin and subcutaneous tissues. LS is responsive to UVA‐1 phototherapy, though its exact mechanism of action dermal fibrosis is yet to be fully elucidated.
Tognetti L +6 more
europepmc +2 more sources
Role of imaging in morphea assessment: A review of the literature. [PDF]
Skin Res Technol, 2023 Abstract Background Localized scleroderma, known as morphea, is a connective tissue disorder characterized by inflammation and fibrosis of the skin and the soft tissue. There exist no universally accepted validated outcome measures in order to monitor the disease activity.
Khorasanizadeh F +2 more
europepmc +2 more sources
UVA-1 phototherapy as adjuvant treatment for eosinophilic fasciitis: in vitro and in vivo functional characterization. [PDF]
Int J Dermatol, 2022 Abstract Introduction Eosinophilic fasciitis (EF) is a rare autoimmune disease causing progressive induration of dermal, hypodermal, and muscularis fascia. The exact pathogenesis is yet to be fully understood, and a validated therapy protocol still lacks. We here aimed to realize a clinical–functional characterization of these patients.
Tognetti L +8 more
europepmc +2 more sources
Intravenous immunoglobulin for the treatment of morphea in pediatric patients: A case series [PDF]
JAAD Case ReportsMilica Milakovic +2 more
exaly +2 more sources
Gluten-Free Diet in Children with Dermatologic Pathology
Педиатрическая фармакология, 2022 Background. Gluten-free diet (GFD) is a nutritional pattern that excludes such component of grain crops as gluten. This diet administration should be strictly regulated due to its influence on the growing child nutritional status and on the course of ...
Leonid A. Opryatin +2 more
doaj +1 more source
Quality of Life in Patients with Morphea: A Cross-Sectional Study and a Review of the Current Literature. [PDF]
Biomed Res Int, 2020 Introduction. Morphea (or localized scleroderma) is an inflammatory, immune‐mediated disease of unknown etiology. It is characterized by excessive collagen deposition that leads to hardening of the dermis, subcutaneous tissues, or both. Morphea is associated with cosmetic and functional impairment, which might affect the patients’ quality of life (QoL).
Szczęch J +4 more
europepmc +2 more sources
Juvenile Localized Scleroderma. Questions of Treatment
Вопросы современной педиатрии, 2020 Juvenile localized scleroderma (JLS) is a group of childhood diseases with the main symptom — skin and subcutaneous structures lesions, without any organ involvement. There is active (inflammatory) and fibrotic phase in development of JLS.
Rinat K. Raupov, Mikhail M. Kostik
doaj +1 more source
Fractional erbium:yttrium aluminum garnet laser in the treatment of morphea mouse model
Journal of Cosmetic Dermatology, Volume 22, Issue 12, Page 3282-3290, December 2023., 2023 Abstract Objective To assess the efficiency and the mechanism of fractional erbium:yttrium aluminum garnet (Er:YAG) laser for the treatment of morphea in mouse model. Background Morphea is a rare autoimmune disease characterized by excessive collagen deposition in skin.
Qing Guo +5 more
wiley +1 more source
High-frequency ultrasound evaluation of morphea: Retrospective analytical study.
Skin Res TechnolAbstract Background To date, there are no accepted outcome measures to monitor morphea, and consensus on specific monitoring criteria for morphea remains elusive. A few studies have assessed the criterion validity of skin ultrasound in morphea. So, in this study, we approach ultrasound findings in morphea lesions.
Yazdanparast T +4 more
europepmc +2 more sources