Results 121 to 130 of about 21,668 (282)

Coupling of Er3+ ions and Plasmonic Modes in Vertical Nanocavities for Spectral Broadening in Telecom Bands

Advanced Materials Technologies, EarlyView.
Left: Illustration of the glass & nanostructures system and the NIR emission at 1.5 µm, where the colored spheres represent the Er3+ ions within the doped glass. Right: Representation of the Stark splitting of the 4I13/2 and 4I15/2 manifolds of the Er3+, illustrating how the plasmonic modes facilitate the emission from the broader Stark manifold ...
Gaston Lozano Calderón, Víctor Anthony García Rivera, Stéphan Cagnon, Souleymane Toubou Bah, Younès Messaddeq, Euclydes Marega Junior   +5 more
wiley   +1 more source

Coupling configurations between extended surface electromagnetic waves and localized surface plasmons for ultrahigh field enhancement

Nanophotonics, 2018
Local enhancement of electromagnetic (EM) fields near dielectric and metallic surfaces is usually associated with the existence of a confined EM wave at least in one direction. This phenomenon finds applications in enhancing optical spectroscopic signals,
Abdulhalim Ibrahim
doaj   +1 more source

Strong Plasmon–Exciton Coupling Tuned by Corner Etching of Gold Nanocubes and Nanotriangles

Advanced Optical Materials, EarlyView.
Systematic etching of gold nanocubes (AuNCs) and nanotriangles (AuNTs) reveals how nanoparticle morphology governs plasmon–exciton strong coupling. While rounding the corners of AuNCs weakens their coupling, triangular geometries robustly preserve deep strong coupling.
Jiyeon Lee, Seoyoung Hwang, Yoon‐Min Lee, Jeong‐Eun Park, Sangwoon Yoon   +4 more
wiley   +1 more source

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

Numerical Investigation of Localized Surface Plasmons in Gold Nano-Ridge Dimer-on-Mirror Structures

Photonics
The study of localized surface plasmons (LSPs) in nanoscale structures is an essential step towards identifying optimal plasmonic modes that can facilitate robust optomechanical coupling and deepen our understanding of light–matter interactions at the ...
Mohamed El Ghafiani, Adnane Noual, Madiha Amrani, Mohammed Moutaouekkil, El Houssaine El Boudouti   +4 more
doaj   +1 more source

A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis

Advanced Science, EarlyView.
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou, Yinghua Ma, Qin Liu, Dingling Ma, Yuxin Tong, Lili Xu, Xiaolong Chu, Jingzhou Wang, Maodi Liang, Mengyuan Zhao, Huizi Zhang, Yurui Su, Jianxin Xie, Cuizhe Wang, Jun Zhang   +14 more
wiley   +1 more source

Halofuginone is a Molecular Glue Degrader of Integrin β4

Advanced Science, EarlyView.
Integrin β4 overexpression is linked to aggressive tumors and poor prognosis, but targeted therapies are lacking. We identified halofuginone (HF) as a molecular glue degrader that promotes integrin β4 degradation via the CRL4BWDR18 E3 ligase. HF suppresses tumor progression in vitro and in vivo, offering a new strategy for targeting oncogenic ...
Wei Gong, Di Yang, Junrui Tian, Yufei Chai, Tiantian Yu, Qingnan Wu, Yan Wang, Weimin Zhang, Qimin Zhan   +8 more
wiley   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

Advanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang, Zhaxi Zerang, Linjin You, Ziye Liu, Rong Nie, Fuwei Qi, Fenfen Gao, Chengmu Zhao, Wantong Ma, Jinghan He, Xiaoru Wang, Shanquan Wu, Bo Liu, Xinyao Liu, Dongsheng Lei, Dejuan Zhi, Dongsheng Wang   +16 more
wiley   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source