Results 91 to 100 of about 5,418,708 (164)

Clinical evaluation and regression test of a commercial deep‐learning auto‐segmentation model

Journal of Applied Clinical Medical Physics, Volume 27, Issue 10, October 2026.
Abstract Background Commercial deep‐learning segmentation (DLS) tools are increasingly used in clinical practice. Software updates may alter segmentation performance, highlighting the need for systematic clinical evaluation before implementation. Purpose This study presents our experience in clinically evaluating and regression‐testing a RayStation DLS
Roya Barati, Jingwei Duan, Song Gao, Yao Zhao, Xinru Chen, Cenji Yu, Zhan Xu, Moghadaseh Khaleghibizaki, Fredrik Lofman, Jared Ohrt, Laurence Court, Peter Balter, Jinzhong Yang   +12 more
wiley   +1 more source

Locally Advanced Pancreatic Cancer: Work-Up, Staging, and Local Intervention Strategies

, 2019
Locally advanced pancreatic cancer (LAPC) has several definitions but essentially is a nonmetastasized pancreatic cancer, in which upfront resection is considered not beneficial due to extensive vascular involvement and consequent high chance of a ...
Dutch Pancreatic Cancer Group and International Collaborative Group on Locally Advanced Pancreatic Cancer
core  

The 9th Edition of the UICC TNM Classification of Malignant Tumours: Updates and Rationale for Change

International Journal of Cancer, Volume 159, Issue 7, Page 1588-1601, 1 October 2026.
ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley, Liesbet J. Van Eycken, Meredith E. Giuliani, Brian A. Rous, Shao Hui Huang, Hisao Asamura, Mary K. Gospodarowicz, Anne W. Lee, Brian O'Sullivan   +8 more
wiley   +1 more source

Surgical outcome following Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer. [PDF]

, 2008
INTRODUCTION : The potential for curative resection is the most important component of the multimodality management of rectal cancer. In locally advanced rectal cancer lymph node involvement and positive resection margins are common, leading to local ...
Yamini Chitra, V
core  

Trends, Disparities, and Outcomes in Time to Treatment Initiation in Patients With Early‐Onset Colorectal Cancer

JGH Open, Volume 10, Issue 10, October 2026.
ABSTRACT Aims The incidence of early‐onset colorectal cancer (EOCRC) is on the rise globally. It is well documented in the literature that increased time to treatment initiation (TTI) results in higher mortality rates in malignancies. We conducted this study to explore trends, disparities, and outcomes in TTI in patients with EOCRC.
Imran Qureshi, Charmi Patel, Muhammad Ali Ibrahim Kazi, Jackson Edwards, Hamza Khan, Kaveh Hajifathalian, Ahmed Al‐Khazraji   +6 more
wiley   +1 more source

Radiological Tumor Calcification in Sinonasal Adenocarcinoma: Prevalence and Prognostic Implications

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 5, October 2026.
Radiological intratumoral calcifications in sinonasal adenocarcinoma have been scarcely investigated. This study aimed to assess their prevalence and evaluate their potential prognostic significance and to examine its association with surgical resectability. ABSTRACT Objective(s) Radiological intratumoral calcifications in sinonasal adenocarcinoma have
Julia Fanchette, Florian Chatelet, Melania Bertolini, B. Boukebous, Alessandro Vinciguerra, Martina Conti, Jean Pierre Guichard, Khaled Al Tabaa, Michel Wassef, Homa Adle‐Biassette, Philippe Herman, Benjamin Verillaud   +11 more
wiley   +1 more source

Colorectal Cancer: Epidemiology, Risk Factors, Signaling Pathways, Clinical Features, Screening, Diagnosis, and Management

MedComm, Volume 7, Issue 10, October 2026.
Colorectal cancer is a heterogeneous, adaptive disease shaped by population‐level risk, genomic and epigenetic alterations, tumor ecosystem evolution, and treatment pressure. This review integrates epidemiology, risk factors, signaling networks, clinical presentation, screening, molecular diagnosis, and stage‐ and biomarker‐guided management while ...
Kairui Wan, Ke Tang, Linglong Wang, Qin Tian, Mingwei Zheng, Cheng Qian, Limei Liu   +6 more
wiley   +1 more source

Radiotherapy‐Induced Side Effects: Epidemiology, Pathogenesis, Prevention and Treatments

MedComm, Volume 7, Issue 10, October 2026.
Radiotherapy for malignancies frequently injures the organs’ systems through oxidative stress, fibrosis, inflammation, and vascular damage. This review systematically maps the epidemiology, pathogenesis, and emerging therapies to propose a mechanism‑network‑targeted framework for integrated, personalized care in radiation oncology.
Xiaowen Ma, Xiaoxuan Zhang, Pujun Zhao, Jiaxin Yang, Zhihao Li, Xiaoyang Han, Yixuan Wang, Zhenzhen Cui, Nian Liu, Min Li   +9 more
wiley   +1 more source

Liver Metastases from Colorectal Cancer: From Pathogenesis to Current Treatment

MedComm, Volume 7, Issue 10, October 2026.
The liver is not merely a passive recipient of disseminated tumor cells, but a unique metastatic organ shaped by anatomical, metabolic, and immunological characteristics that support tumor colonization. Increasing evidence indicates that colorectal cancer liver metastasis development is driven by dynamic interactions between tumor intrinsic programs ...
Jialiang Fan, Huiru Zhang, Deyang Kong, Yu Sun, Shuaibing Lu, Wenjing Yang, Renshen Xiang, Qi Zhang, Wei Pei, Haizeng Zhang, Lin Feng   +10 more
wiley   +1 more source

Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response

MedComm, Volume 7, Issue 10, October 2026.
Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu, Jie Yu, Ying Chen, Shengfang Ge, Lin Ye, Yefei Wang, Yixiong Zhou, Renbing Jia   +7 more
wiley   +1 more source