Results 41 to 50 of about 402 (270)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Bounds on Binary Locally Repairable Codes Tolerating Multiple Erasures
Recently, locally repairable codes have gained significant interest for their potential applications in distributed storage systems. However, most constructions in existence are over fields with size that grows with the number of servers, which makes the
Grezet, Matthias +4 more
core +1 more source
Additive manufacturing provides precise control over the placement of continuous fibres within polymer matrices, enabling customised mechanical performance in composite components. This article explores processing strategies, mechanical testing, and modelling approaches for additive manufactured continuous fibre‐reinforced composites.
Cherian Thomas, Amir Hosein Sakhaei
wiley +1 more source
Locally Repairable Regenerating Code Constructions
6 ...
Imad Ahmad, Chih-Chun Wang
openaire +2 more sources
PASTA‐ELN: Simplifying Research Data Management for Experimental Materials Science
Research data management faces ongoing hurdles as many ELNs remain complex and restrictive. PASTA‐ELN offers an open‐source, cross‐platform solution that prioritizes simplicity, offline access, and user control. Its in tuitive folder structure, modular Python add‐ons, and open formats enable seamless documentation, FAIR data practices, and easy ...
S. Brinckmann, G. Winkens, R. Schwaiger
wiley +1 more source
Upper bounds on maximum lengths of Singleton-optimal locally repairable codes
A locally repairable code is called Singleton-optimal if it achieves the Singleton-type bound. Such codes are of great theoretic interest in the study of locally repairable codes.
Wu, Tingyi +3 more
core
3D Printing Innovations in Polymeric Porous and Patterned Architecture
Polymeric foams occupy a unique structural space between dense solids and open networks, where engineered void fraction governs mechanical compliance, thermal resistance, and mass transport. Additive manufacturing now enables precise spatial control over cellular architecture, unlocking designer foam structures across applications spanning crash ...
Dhanush Patil +13 more
wiley +1 more source
Modern distributed storage systems increasingly employ Locally Repairable Codes (LRCs) to provide reliable, low-cost data storage with high repair efficiency.
Ximeng Chen, Si Wu, Yinlong Xu
doaj +1 more source
On the Combinatorics of Locally Repairable Codes via Matroid Theory
This paper provides a link between matroid theory and locally repairable codes (LRCs) that are either linear or more generally almost affine. Using this link, new results on both LRCs and matroid theory are derived.
Westerbäck, Thomas, +7 more
core +1 more source

