Results 91 to 100 of about 4,226,378 (303)

ISPC Commentary on the Proposal for CRP3.3 - July 2010

open access: yes, 2023
Initial comments from the interim Independent Science and Partnership Council on the proposal for CRP 3.3: GRiSP, Global Rice Science Partnership - the first fast tracked CGIAR Mega Program ...
CGIAR Independent Science and Partnership Council
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Smartphone-Based Body Location-Independent Functional Mobility Analysis in Patients with Parkinson's Disease: A Step towards Precise Medicine. [PDF]

open access: yesJ Pers Med, 2022
Vila-Viçosa D   +6 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Outcome measurement instruments for the core outcome sets on genital gender-affirming surgery: the GenderCOS projectResearch in context

open access: yesEClinicalMedicine
Summary: Background: Outcome assessment in genital gender-affirming surgery (gGAS) has long been a heterogenous practice. Although two core outcome sets (COS) for masculinizing and feminizing gGAS have been previously established, the absence of ...
Matteo Angelini   +15 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Oregon's Interagency Compliance Network

open access: yes, 2011
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on Jan.

core  

Price-forming factors choice grounding at intangible assets with negative depreciation independent valuation/appraising

open access: yes, 2020
Independent expert valuation/appraising of intellectual property rights objects, such as brands and goodwill, performed by the Costs approach, is based on economic indicators of these intangible assets utility degree, which are connected with the sum of ...
Zoryana, Skybinska   +2 more
core  

LUTI models, freight transport and freight facility location [PDF]

open access: yes, 2016
The subject of this book is the new scientific research in the field of modelling the interaction between land use and transport (LUTI modelling). Transport and the location of activities in space have been important themes of study in engineering ...
Nuzzolo, A., Comi, A., Papa, E.
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