Results 61 to 70 of about 1,114,000 (268)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Fault diagnosis and location of independent sub-module of three-phase MMC based on the optimal deep BiD-LSTM networks

Energy Reports, 2022
Modular multilevel converter (MMC), which is highly modular, easy to be expanded, and has good output voltage waveform, is especially suitable for medium and high voltage power system applications.
Bo Xu, Cui Li, Huipeng Li, Ruchun Ding
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Regulation of epithelial growth factor receptors by the oncoprotein E5 during the HPV16 differentiation-dependent life cycle

Tumour Virus Research
Human papillomavirus (HPV) 16 infection initiates upon viral entry into the basal cells of the epithelium. The virus manipulates signaling pathways to complete its life cycle, which depends on cellular differentiation.
Mariano A. Molina, Sneha Biswas, Omar Jiménez-Vázquez, Jason M. Bodily   +3 more
doaj   +1 more source

Remote working in academia: a site of contested identities. [PDF]

, 2018
This development paper discusses the affects and impact of formalised remote (location-independent) working on notions and construction of academic identity. Data is drawn from a six year longitudinal ethnographic study exploring the lived experiences of
Lee, Amanda
core   +1 more source

Efficient Batch Update of Unique Identifiers in a Distributed Hash Table for Resources in a Mobile Host [PDF]

, 2010
Resources in a distributed system can be identified using identifiers based on random numbers. When using a distributed hash table to resolve such identifiers to network locations, the straightforward approach is to store the network location directly in
Chung, Yoo
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

CRACK LOCALIZATION IN HYDRAULIC TURBINE BLADES BASED ON KERNEL INDEPENDENT COMPONENT ANALYSIS AND WAVELET NEURAL NETWORK [PDF]

International Journal of Computational Intelligence Systems, 2013
Hydraulic turbine runner has a complex structure, and traditional location methods can't meet its requirement. This paper describes a source location of cracks in turbine blades by combining kernel independent component analysis (KICA) with wavelet ...
Xianghong Wang, Hanling Mao, Hongwei Hu, Zhiyong Zhang   +3 more
doaj   +1 more source

A Scalable Location Service for Distributed Objects [PDF]

, 1996
We describe a service for locating distributed objects using location-independent object identifiers. An object in our model is physically distributed, with multiple copies simultaneously active on different machines.
Hauck, F.J., Steen, M. van, Tanenbaum, A.S.   +2 more
core   +6 more sources

Towards an Efficient Context-Aware System: Problems and Suggestions to Reduce Energy Consumption in Mobile Devices [PDF]

, 2010
Looking for optimizing the battery consumption is an open issue, and we think it is feasible if we analyze the battery consumption behavior of a typical context-aware application to reduce context-aware operations at runtime.
Ardito, Luca, Falcarin, Paolo, Mejia Bernal, Jose Felipe, Morisio, Maurizio   +3 more
core   +1 more source