Results 1 to 10 of about 7,088,945 (316)

Evening aspirin intake results in higher levels of platelet inhibition and a reduction in reticulated platelets - a window of opportunity for patients with cardiovascular disease?

Platelets, 2021
Cardiovascular events occur most frequently in the early morning. Similarly, the release of reticulated platelets (RP) by megakaryocytes has a peak in the late night and early morning.
J.J.K. van Diemen, M.C. Madsen, P. Vrancken, K. de Bie, J.G. van der Bom, G. Veen, T.N. Bonten, W.W. Fuijkschot, Y.M. Smulders, A. Thijs   +9 more
doaj   +1 more source

The INVENT COVID trial: a structured protocol for a randomized controlled trial investigating the efficacy and safety of intravenous imatinib mesylate (Impentri®) in subjects with acute respiratory distress syndrome induced by COVID-19

Trials, 2022
Background The coronavirus disease 2019 (COVID-19) pandemic has led to a disruptive increase in the number of intensive care unit (ICU) admissions with acute respiratory distress syndrome (ARDS).
Leila Atmowihardjo, Job R. Schippers, Imke H. Bartelink, Pierre M. Bet, Nienke van Rein, Keith Purdy, David Cavalla, Valérie Comberiati, Andrew McElroy, Sue D. Snape, Harm Jan Bogaard, Leo Heunks, Nicole Juffermans, Marcus Schultz, Pieter R. Tuinman, Lieuwe D. J. Bos, Jurjan Aman   +16 more
doaj   +1 more source

Broadening the Berlin definition of ARDS to patients receiving high-flow nasal oxygen: an observational study in patients with acute hypoxemic respiratory failure due to COVID-19

Annals of Intensive Care, 2023
Background High-flow nasal oxygen (HFNO) is increasingly used in patients with acute hypoxemic respiratory failure. It is uncertain whether a broadened Berlin definition of acute respiratory distress syndrome (ARDS), in which ARDS can be diagnosed in ...
Fleur-Stefanie L. I. M. van der Ven, Christel M. A. Valk, Siebe Blok, Michelle G. Brouwer, Dai Ming Go, Amanda Lokhorst, Pien Swart, David M. P. van Meenen, Frederique Paulus, Marcus J. Schultz, for the PRoAcT–COVID study investigators   +10 more
doaj   +1 more source

DIONYSIUS trial: “Does increasing oxygen nurture your symptomatic ischaemic ulcer sufficiently?” Study protocol for an international multicentre randomised trial

BMJ Open, 2023
Introduction Diabetic foot ulcers (DFUs) are a major complication of diabetes and often associated with peripheral arterial occlusive disease. Current available evidence shows hyperbaric oxygen therapy (HBOT) can reduce the risk of major amputation, but ...
Rigo Hoencamp, Susan Van Dieren, Dirk Ubbink, Mark Koelemay, Robin Brouwer, Rowan van der Peet, Rob van Hulst   +6 more
doaj   +1 more source

Prescribing errors in post - COVID-19 patients: prevalence, severity, and risk factors in patients visiting a post - COVID-19 outpatient clinic

BMC Emergency Medicine, 2022
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), has challenged healthcare globally.
Rashudy F. Mahomedradja, Tessa O. van den Beukel, Maaike van den Bos, Steven Wang, Kirsten A. Kalverda, Birgit I. Lissenberg-Witte, Marianne A. Kuijvenhoven, Esther J. Nossent, Majon Muller, Kim C. E. Sigaloff, Jelle Tichelaar, Michiel A. van Agtmael   +11 more
doaj   +1 more source

Minimal invasive aortic valve replacement: associations of radiological assessments with procedure complexity

Journal of Cardiothoracic Surgery, 2019
Objectives Limited aortic annulus exposure during minimal invasive aortic valve replacement (mini-AVR) proves to be challenging and contributes to procedure complexity, resulting in longer procedure times. New innovations like sutureless valves have been
Bruce R. Boti, Vikash G. Hindori, Emilio L. Schade, Athina M. Kougioumtzoglou, Eva C. Verbeek, Annet Driessen-Waaijer, Riccardo Cocchieri, Bas A. J. M. de Mol, Nils R. Planken, Abdullah Kaya, Henk A. Marquering   +10 more
doaj   +1 more source

PalliSupport – The development, feasibility and implementation of a transitional integrated care pathway for older patients with palliative care needs

International Journal of Integrated Care, 2019
Introduction - Marjon van Rijn (5 minutes): For the development, implementation and evaluation of a transitional integrated care pathway for older patient with palliative care needs we used the Medical Research (MRC) Framework.
Marjon van Rijn, Isabelle Flierman, Dick Willems, Bianca Buurman   +3 more
doaj   +1 more source

BIRC2–BIRC3 amplification: a potentially druggable feature of a subset of head and neck cancers in patients with Fanconi anemia

Scientific Reports, 2022
Head-and-neck squamous cell carcinomas (HNSCCs) are relatively common in patients with Fanconi anemia (FA), a hereditary chromosomal instability disorder.
Khashayar Roohollahi, Yvonne de Jong, Govind Pai, Mohamad Amr Zaini, Klaas de Lint, Daoud Sie, Martin A. Rooimans, Davy Rockx, Elizabeth E. Hoskins, Najim Ameziane, Rob Wolthuis, Hans Joenje, Susanne I. Wells, Josephine Dorsman   +13 more
doaj   +1 more source

Cardiac thrombus dissolution in acute ischemic stroke: A substudy of Mind the Heart

Heliyon, 2023
Background: Cardiac thrombi are an important cause of ischemic stroke but are infrequently detected on cardiac imaging. We hypothesized that this might be explained by early dissolution of these cardiac thrombi after stroke occurrence.
C.F.P. Beemsterboer, L.A. Rinkel, V. Guglielmi, N.-S. Groeneveld, N.H.J. Lobé, S.M. Boekholdt, B.J. Bouma, F.F. Muller, L.F.M. Beenen, H.A. Marquering, C.B.L.M. Majoie, Y.B.W.E.M. Roos, A. van Randen, R.N. Planken, J.M. Coutinho   +14 more
doaj   +1 more source

EMDR therapy for misophonia: a pilot study of case series

European Journal of Psychotraumatology, 2021
Background: Misophonia is a disorder in which patients suffer from anger or disgust when confronted with specific sounds such as loud chewing or breathing, causing avoidance of cue-related situations resulting in significant functional impairment. Though
Inge Jager, Nienke Vulink, Carlijn de Roos, Damiaan Denys   +3 more
doaj   +1 more source