Results 31 to 40 of about 8,859,889 (261)

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

Effect of long-term antihypertensive treatment on cerebrovascular structure and function in hypertensive rats

Scientific Reports, 2023
Midlife hypertension is an important risk factor for cognitive impairment and dementia, including Alzheimer’s disease. We investigated the effects of long-term treatment with two classes of antihypertensive drugs to determine whether diverging mechanisms
Daphne M. P. Naessens, Judith de Vos, Edo Richard, Micha M. M. Wilhelmus, Cornelis A. M. Jongenelen, Edwin R. Scholl, Nicole N. van der Wel, Johannes A. Heijst, Charlotte E. Teunissen, Gustav J. Strijkers, Bram F. Coolen, Ed VanBavel, Erik N. T. P. Bakker   +12 more
doaj   +1 more source

Protein (Multi-)Location Prediction: Using Location Inter-Dependencies in a Probabilistic Framework

, 2013
Knowing the location of a protein within the cell is important for understanding its function, role in biological processes, and potential use as a drug target. Much progress has been made in developing computational methods that predict single locations
Shatkay, Hagit, Simha, Ramanuja
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

The daily practice of (suspected) coeliac disease management by general practitioners: A qualitative approach

European Journal of General Practice, 2018
Background: General practitioners (GPs) play a crucial role in diagnosing coeliac disease (CD). However, data on GP management of (suspected) CD patients is sparse.
Tom van Gils, Talha G. Senler, Henriëtte E. van der Horst, Chris J.J. Mulder, Gerd Bouma, Henk de Vries   +5 more
doaj   +1 more source

Early hyperbaric oxygen therapy is associated with favorable outcome in patients with iatrogenic cerebral arterial gas embolism: systematic review and individual patient data meta-analysis of observational studies

Critical Care, 2023
Background Iatrogenic cerebral arterial gas embolism (CAGE) caused by invasive medical procedures may be treated with hyperbaric oxygen therapy (HBOT). Previous studies suggested that initiation of HBOT within 6–8 h is associated with higher probability ...
Raoul A. Fakkert, Noa Karlas, Patrick Schober, Nina C. Weber, Benedikt Preckel, Robert A. van Hulst, Robert P. Weenink   +6 more
doaj   +1 more source

Location spoofing [PDF]

, 2004
The ability to blur and lie about our location does deserve consideration and should not be treated as entirely malevolent. It will be up to designers to allow the user to have full responsibility and freedom over the access control of their location ...
Glassey, Richard
core  

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas

Blood Cancer Journal, 2023
The paracaspase mucosa-associated lymphoid tissue 1 (MALT1) is a protease and scaffold protein essential in propagating B-cell receptor (BCR) signaling to NF-κB.
Marthe Minderman, Hildo C. Lantermans, Leonie J. Grüneberg, Saskia A. G. M. Cillessen, Richard J. Bende, Carel J. M. van Noesel, Marie José Kersten, Steven T. Pals, Marcel Spaargaren   +8 more
doaj   +1 more source

'Location, Location, Location' : effects of neighborhood and house attributes on Burglars’ target selection [PDF]

, 2019
Objectives To empirically test whether offenders consider environmental features at multiple spatial scales when selecting a target and examine the simultaneous effect of neighborhood-level and residence-level attributes on residential burglars' choice ...
Bernasco, Wim, Vandeviver, Christophe
core   +3 more sources